Gastroenterology
Volume 137, Issue 1 , Pages 350-360.e5, July 2009

Impaired Autolysosome Formation Correlates With Lamp-2 Depletion: Role of Apoptosis, Autophagy, and Necrosis in Pancreatitis

  • Franco Fortunato

      Affiliations

    • Department of General, Visceral, and Transplantation Surgery, University Hospital Heidelberg, Germany
    • Corresponding Author InformationReprint requests Address requests for reprints to: Franco Fortunato, PhD, University Hospital Heidelberg, Department of General, Visceral, and Transplantation Surgery, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany. fax: (49) 6221-56 4542
  • ,
  • Heinrich Bürgers

      Affiliations

    • Department of Physiology and Pathophysiology, University Hospital Heidelberg, Germany
  • ,
  • Frank Bergmann

      Affiliations

    • Department of Pathology, University Hospital Heidelberg, Germany
  • ,
  • Peter Rieger

      Affiliations

    • Department of Pathology, University Hospital Heidelberg, Germany
  • ,
  • Markus W. Büchler

      Affiliations

    • Department of General, Visceral, and Transplantation Surgery, University Hospital Heidelberg, Germany
  • ,
  • Guido Kroemer

      Affiliations

    • INSERM U848, Villejuf, France
    • Institut Gustave Roussy, Villejuf, France
    • Université Paris Sud, Villejuf, France
  • ,
  • Jens Werner

      Affiliations

    • Department of General, Visceral, and Transplantation Surgery, University Hospital Heidelberg, Germany

Received 23 May 2008; accepted 2 April 2009. published online 10 April 2009.

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 H.B.'s present address is TissueGnostics GmbH, Vienna, Austria.

 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by a European Union Marie Curie award and by institutional funding (to F.F.) as well as by Agence National de Recherche (to G.K.).

PII: S0016-5085(09)00527-7

doi:10.1053/j.gastro.2009.04.003

Gastroenterology
Volume 137, Issue 1 , Pages 350-360.e5, July 2009