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Gastroenterology
Volume 136, Issue 5
, Pages 1490-1492
, May 2009
High- or Low-Carbohydrate Diets: Which Is Better for Weight Loss, Insulin Resistance, and Fatty Livers?
References
- Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002;288:1723–1727
- . Popular diets: a scientific review. Obes Res. 2001;9(Suppl 1):1S–40S
- . Dr. Atkins' new diet revolution. New York: Avon Books; 1992;
- Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology. 2009;136:1552–1560
- Effect of a low-carbohydrate diet on appetite, blood glucose levels and insulin resistance in obese patients with type 2 diabetes. Ann Intern Med. 2005;142:403–411
- . Composition of weight lost during short-term weight reduction (Metabolic responses of obese subjects to starvation and low-calorie ketogenic and nonketogenic diets). J Clin Invest. 1976;58:722–730
- A low-carbohydrate as compared with a low-fat diet in severe obesity. N Engl J Med. 2003;348:2074–2081
- Randomized trial of a low-carbohydrate diet for obesity. N Engl J Med. 2003;348:2082–2090
- A randomized trial comparing very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women. J Clin Endocrinol Metab. 2003;88:1617–1623
- The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med. 2004;140:778–785
- . Popular weight-loss diets; from evidence to practice. Nat Clin Pract Cardiovasc Med. 2007;4:34–41
- Calories do count. Metabolism. 1964;13:195–204
- Effect of amino acids and protein on insulin secretion in man. Rec Prog Horm Res. 1967;23:617–656
- Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects. Am J Physiol. 1996;270:E251–E258
- . Dose-response characteristics for effects of insulin on production and utilization of glucose in man. Am J Physiol. 1981;240:E630
- . Nonalcoholic fatty liver disease. N Engl J Med. 2002;346:1221–1231
- . Contribution of adipose tissue and de novo lipogenesis to nonalcoholic fatty liver disease. J Clin Invest. 2005;115:1139–1142
- . Molecular mediators of hepatic steatosis and liver injury. J Clin Invest. 2004;114:147–152
- Decreased IRS-2 and increased SREBP-1 lead to mixed insulin resistance and sensitivity in livers and lipodystrophic and ob/ob mice. Mol Cell. 2000;6:77–86
- . Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver. J Biol Chem. 2001;276:9437–9554
- . Recent findings concerning thiazolidinediones in the treatment of diabetes. Expert Opin Investig Drugs. 2006;15:243–250
- Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci U S A. 2004;101:6659–6663
Conflicts of interest The author discloses no conflicts.
Funding Supported by National Institutes of Health grants R01-DK58895, HL-0733267, and R01-DK066003 and a grant from the Groff Foundation.
PII: S0016-5085(09)00451-X
doi: 10.1053/j.gastro.2009.03.019
© 2009 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 136, Issue 5
, Pages 1490-1492
, May 2009

