Probe-Based Confocal Laser Endomicroscopy

published online 31 March 2009.

Confocal laser endomicroscopy is a new field of endoluminal imaging that offers extremely high magnification and resolution, approximating white light microscopy. This has the potential to fundamentally change the current algorithms of gastroenterologic diagnosis. A recent consensus conference (International Conference of Cellvizo Users, Miami, FL, Feb 22–23, 2009) on probe-based confocal laser endomicroscopy (pCLE) held in February 2009, established basic indications, techniques, research priorities and standards for image interpretation. This article summarizes the findings of that meeting.

Michael B. Wallace, Section Editor

Abbreviations used in this paper: BE, Barrett's esophagus, eCLE, endoscope-based confocal laser endomicroscopy, IBD, inflammatory bowel disease, IEN, intraepithelial neoplasia, NPV, negative predictive value, pCLE, probe-based confocal laser endomicroscopy

⁎ Mayo Clinic, Jacksonville, Florida

‡ Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Reprint requests Address requests for reprints to: Michael B. Wallace, MD, MPH, Professor of Medicine, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, Florida 32224

Conflicts of interest Dr Wallace receives research funding from Mauna Kea Technologies but no consulting or speaker's bureau fees.

PII: S0016-5085(09)00438-7

doi:10.1053/j.gastro.2009.03.034

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