Gastroenterology
Volume 136, Issue 7 , Pages 2325-2333 , June 2009

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

  • Aline Antoniou

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Peggy Raynaud

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Sabine Cordi

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Yiwei Zong

      Affiliations

    • Division of Gastroenterology, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • François Tronche

      Affiliations

    • CNRS UMR 7148, Institut de Biologie, Collège de France, Paris, France
    • ,
  • Ben Z. Stanger

      Affiliations

    • Division of Gastroenterology, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    • ,
  • Patrick Jacquemin

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Christophe E. Pierreux

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Frederic Clotman

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • ,
  • Frederic P. Lemaigre

      Affiliations

    • Université catholique de Louvain, de Duve Institute, Brussels, Belgium
    • Corresponding Author InformationReprint requests Address requests for reprints to: F. P. Lemaigre, MD, Université catholique de Louvain, de Duve Institute, Avenue Hippocrate 75/7529, 1200 Brussels, Belgium. fax: (32) 2 764 7507

Received 28 August 2008 ,Accepted 6 February 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by the Interuniversity Attraction Poles Program (Belgian Science Policy; to F.L.), the D.G. Higher Education and Scientific Research of the French Community of Belgium (to F.L.), the Alphonse and Jean Forton Fund (to F.L.), and the Fund for Scientific Medical Research (to F.L.); and by NIH grant DK076583 (to B.Z.S.).A.A. and P.R. hold fellowships from the Université catholique de Louvain. F.C., C.P., and P.J. are research associates of the F.R.S.-F.N.R.S.

PII: S0016-5085(09)00300-X

doi: 10.1053/j.gastro.2009.02.051

Gastroenterology
Volume 136, Issue 7 , Pages 2325-2333 , June 2009

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