Gastroenterology
Volume 136, Issue 3 , Pages 757-760 , March 2009

Striving for Abstinence in Alcoholic Pancreatitis: Act of Humanity, Economic Necessity, or Flogging a Dead Horse After All?

  • Manfred V. Singer

      Affiliations

    • Department of Medicine II (Gastroenterology, Hepatology and Infectious Diseases), University Hospital of Mannheim, University of Heidelberg, Mannheim, Germany
    • Corresponding Author InformationReprint requests Address requests for reprints to: Manfred V. Singer, MD (Hon. Doc. mult.), Department of Medicine II (Gastroenterology, Hepatology and Infectious Diseases), University Hospital of Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany; fax +49-621/383-3805
  • ,
  • Roland H. Pfützer

      Affiliations

    • Department of Medicine II (Gastroenterology, Hepatology and Infectious Diseases), University Hospital of Mannheim, University of Heidelberg, Mannheim, Germany
  • ,
  • Falk Kiefer

      Affiliations

    • Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health (CIMH) Mannheim, University of Heidelberg, Mannheim, Germany

References 

  1. Rehm J, Room R, Monteiro M, et al. Alcohol use. In:  Ezzati M,  Lopez AD,  Rodgers A editor. Comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors. vol 1:Geneva: World Health Organization; 2004;p. 959–1106
  2. National Institute on Alcohol Abuse and Alcoholism. Five year strategic plan FY09-14 (Alcohol across the lifespan). http://www.niaaa.nih.gov/NR/rdonlyres/F839E0D5-7247-4D30-A816-26DD5EBADF40/0/StrategicPlan2006.pdf
  3. Gerke P, Hapke U, Rumpf HJ, et al. Alcohol-related diseases in general hospital patients. Alcohol Alcohol. 1997;32:179–184
  4. Nordback I, Pelli H, Lappalainen-Lehto R, et al. The recurrence of acute alcohol-associated pancreatitis can be reduced—a randomized controlled trial. Gastroenterology. 2009;136:848–855
  5. Kalaitzakis E, Wallskog J, Bjornsson E. Abstinence in patients with alcoholic liver cirrhosis: a follow-up study. Hepatol Res. 2008;38:869–876
  6. Heinz A, Wilwer M, Mann K. Therapy and supportive care of alcoholics: guidelines for practitioners. Best Pract Clin Gastroenterol. 2003;17:695–708
  7. Hanck C, Singer MV. Does acute alcoholic pancreatitis exist without preexisting chronic pancreatitis?. Scand J Gastroenterol. 1997;32:625–626
  8. Witt H, Apte MV, Keim V, et al. Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy. Gastroenterology. 2007;132:1557–1573
  9. Sarles H. Chronic calcifying pancreatitis—chronic alcoholic pancreatitis. Gastroenterology. 1974;66:604–616
  10. Strum WB. Abstinence in alcoholic chronic pancreatitis (Effect on pain and outcome). J Clin Gastroenterol. 1995;20:37–41
  11. Lowenfels AB, Maisonneuve P, Cavallini G, et al. Prognosis of chronic pancreatitis: an international multicenter study (International Pancreatitis Study Group). Am J Gastroenterol. 1994;89:1467–1471
  12. Andersson R, Andersson B, Haraldsen P, et al. Incidence, management and recurrence rate of acute pancreatitis. Scand J Gastroenterol. 2004;39:891–894
  13. Gullo L, Migliori M, Pezzilli R, et al. An update on recurrent acute pancreatitis: data from five European countries. Am J Gastroenterol. 2002;97:1959–1962
  14. Maisonneuve P, Lowenfels AB, Müllhaupt B, et al. Cigarette smoking accelerates progression of alcoholic chronic pancreatitis. Gut. 2005;54:510–514
  15. Wittel UA, Pandey KK, Andrianifahanana M, et al. Chronic pancreatic inflammation induced by environmental tobacco smoke inhalation in rats. Am J Gastroenterol. 2006;101:148–159
  16. Mann K, Schäfer DR, Längle G, et al. The long-term course of alcoholism, 5, 10 and 16 years after treatment. Addiction. 2005;100:797–805
  17. Madras BK, Compton WM, Avula D, et al. Screening, brief interventions, referral to treatment (SBIRT) for illicit drug and alcohol use at multiple healthcare sites: comparison at intake and 6 months later. Drug Alcohol Depend. 2009;99:280–295
  18. Ockene JK, Adams A, Hurley TG, et al. Brief physician- and nurse practitioner-delivered counseling for high-risk drinkers: does it work?. Arch Intern Med. 1999;159:2198–2205
  19. Kaner EFS, Beyer F, Dickinson HO, et al. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev. 2007;CD004148

 Conflicts of interest The authors disclose no conflicts.

PII: S0016-5085(09)00048-1

doi: 10.1053/j.gastro.2009.01.018

Gastroenterology
Volume 136, Issue 3 , Pages 757-760 , March 2009