Gastroenterology
Volume 136, Issue 3 , Pages 806-815 , March 2009

Alcohol Types and Sociodemographic Characteristics as Risk Factors for Barrett's Esophagus

  • Ai Kubo

      Affiliations

    • Division of Research, Kaiser Permanente, Oakland, California
    • Corresponding Author InformationReprint requests Address requests for reprints to: Ai Kubo, PhD, Kaiser Permanente Division of Research, 2000 Broadway, Oakland, California 94612. fax: (510) 891-3606
    • ,
  • Theodore R. Levin

      Affiliations

    • Division of Research, Kaiser Permanente, Oakland, California
    • ,
  • Gladys Block

      Affiliations

    • School of Public Health, University of California, Berkeley, Berkeley, California
    • ,
  • Gregory J. Rumore

      Affiliations

    • Division of Research, Kaiser Permanente, Oakland, California
    • ,
  • Charles P. Quesenberry Jr

      Affiliations

    • Division of Research, Kaiser Permanente, Oakland, California
    • ,
  • Patricia Buffler

      Affiliations

    • School of Public Health, University of California, Berkeley, Berkeley, California
    • ,
  • Douglas A. Corley

      Affiliations

    • Division of Research, Kaiser Permanente, Oakland, California
    • Department of Medicine, University of California, San Francisco, San Francisco, California

Received 22 August 2008 ,Accepted 20 November 2008.

References 

  1. Pohl H, Welch HG. The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst. 2005;97:142–146
  2. Blot WJ, Devesa SS, Fraumeni JF. Continuing climb in rates of esophageal adenocarcinoma: an update. JAMA. 1993;270:1320
  3. Blot WJ, Devesa SS, Kneller RW, et al. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. Jama. 1991;265:1287–1289
  4. Blot WJ, McLaughlin JK. The changing epidemiology of esophageal cancer. Semin Oncol. 1999;26:2–8
  5. Kubo A, Corley DA. Marked regional variation in adenocarcinomas of the esophagus and the gastric cardia in the United States. Cancer. 2002;95:2096–2102
  6. Kubo A, Corley DA. Marked multi-ethnic variation of esophageal and gastric cardia carcinomas within the United States. Am J Gastroenterol. 2004;99:582–588
  7. Pelucchi C, Gallus S, Garavello W, et al. Cancer risk associated with alcohol and tobacco use: focus on upper aero-digestive tract and liver. Alcohol Res Health. 2006;29:193–198
  8. Gray JR, Coldman AJ, MacDonald WC. Cigarette and alcohol use in patients with adenocarcinoma of the gastric cardia or lower esophagus. Cancer. 1992;69:2227–2231
  9. Brown LM, Silverman DT, Pottern LM, et al. Adenocarcinoma of the esophagus and esophagogastric junction in white men in the United States: alcohol, tobacco, and socioeconomic factors. Cancer Causes Control. 1994;5:333–340
  10. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 1995;4:85–92
  11. Zhang ZF, Kurtz RC, Sun M, et al. Adenocarcinomas of the esophagus and gastric cardia: medical conditions, tobacco, alcohol, and socioeconomic factors. Cancer Epidemiol Biomarkers Prev. 1996;5:761–768
  12. Garidou A, Tzonou A, Lipworth L, et al. Life-style factors and medical conditions in relation to esophageal cancer by histologic type in a low-risk population. Int J Cancer. 1996;68:295–299
  13. Kabat GC, Ng SK, Wynder EL. Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia. Cancer Causes Control. 1993;4:123–132
  14. Lagergren J, Bergstrom R, Adami HO, et al. Association between medications that relax the lower esophageal sphincter and risk for esophageal adenocarcinoma. Ann Intern Med. 2000;133:165–175
  15. Lagergren J, Bergstrom R, Lindgren A, et al. The role of tobacco, snuff and alcohol use in the aetiology of cancer of the oesophagus and gastric cardia. Int J Cancer. 2000;85:340–346
  16. Gammon MD, Schoenberg JB, Ahsan H, et al. Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst. 1997;89:1277–1284
  17. Labenz J, Jaspersen D, Kulig M, et al. Risk factors for erosive esophagitis: a multivariate analysis based on the ProGERD study initiative. Am J Gastroenterol. 2004;99:1652–1656
  18. Lagergren J. Adenocarcinoma of oesophagus: what exactly is the size of the problem and who is at risk?. Gut. 2005;54(Suppl 1):i1–i5
  19. Sharma P, McQuaid K, Dent J, et al. A critical review of the diagnosis and management of Barrett's esophagus: the AGA Chicago Workshop. Gastroenterology. 2004;127:310–330
  20. Reid BJ, Barrett MT, Galipeau PC, et al. Barrett's esophagus: ordering the events that lead to cancer. Eur J Cancer Prev. 1996;5(Suppl 2):57–65
  21. Spechler SJ, Robbins AH, Rubins HB, et al. Adenocarcinoma and Barrett's esophagus (An overrated risk?). Gastroenterology. 1984;87:927–933
  22. Ronkainen J, Aro P, Storskrubb T, et al. Prevalence of Barrett's esophagus in the general population: an endoscopic study. Gastroenterology. 2005;129:1825–1831
  23. Ritenbaugh C, Sampliner R, Aickin M, et al. Risk factors for Barrett's oesophagus: a life history approach to behavioural assessment in the distant past. Eur J Cancer Prev. 1995;4:459–468
  24. Veugelers PJ, Porter GA, Guernsey DL, et al. Obesity and lifestyle risk factors for gastroesophageal reflux disease, Barrett esophagus and esophageal adenocarcinoma. Dis Esophagus. 2006;19:321–328
  25. Conio M, Filiberti R, Blanchi S, et al. Risk factors for Barrett's esophagus: a case-control study. Int J Cancer. 2002;97:225–229
  26. Hirota WK, Loughney TM, Lazas DJ, et al. Specialized intestinal metaplasia, dysplasia, and cancer of the esophagus and esophagogastric junction: prevalence and clinical data. Gastroenterology. 1999;116:277–285
  27. Johansson J, Hakansson HO, Mellblom L, et al. Risk factors for Barrett's oesophagus: a population-based approach. Scand J Gastroenterol. 2007;42:148–156
  28. Corley DA, Kubo A, Levin TR, et al. Abdominal obesity and body mass index as risk factors for Barrett's esophagus. Gastroenterology. 2007;133:34–41
  29. Hiatt RA, Friedman GD. The frequency of kidney and urinary tract diseases in a defined population. Kidney Int. 1982;22:63–68
  30. Krieger N. Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. Am J Public Health. 1992;82:703–710
  31. Kleinbaum D, Kupper L, Morgenstern H. Epidemiologic Research (Principles and Quantitative Methods). New York: Van Nostrand Reinhold; 1982;
  32. Hosmer D, Lameshow S. Applied Logistic Regression. New York: John Wiley and Sons; 2000;
  33. Rothman K, Greenland S. Modern Epidemiology. Philadelphia, PA: Lippincott Williams & Wilkins; 1998;
  34. Zhao Y, Ash A, Ellis R, et al. Predicting pharmacy costs and other medical costs using diagnoses and drug claims. Med Care. 2005;43:34–43
  35. Zhao Y, Ellis RP, Ash AS, et al. Measuring population health risks using inpatient diagnoses and outpatient pharmacy data. Health Serv Res. 2001;36:180–193
  36. Rivero-Perez MD, Muniz P, Gonzalez-Sanjose ML. Antioxidant profile of red wines evaluated by total antioxidant capacity, scavenger activity, and biomarkers of oxidative stress methodologies. J Agric Food Chem. 2007;55:5476–5483
  37. Chen X, Mikhail SS, Ding YW, et al. Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats. Carcinogenesis. 2000;21:1531–1536
  38. Kubo A, Corley DA. Meta-analysis of antioxidant intake and the risk of esophageal and gastric cardia adenocarcinoma. Am J Gastroenterol. 2007;102:2323–2330
  39. Kubo A, Levin TR, Block G, et al. Dietary patterns and the risk of Barrett's esophagus. Am J Epidemiol. 2008;167:839–846
  40. Gronbaek M. Confounders of the relation between type of alcohol and cardiovascular disease. Ann Epidemiol. 2007;17:S13–S15
  41. Gronbaek M, Mortensen EL, Mygind K, et al. Beer, wine, spirits and subjective health. J Epidemiol Community Health. 1999;53:721–724
  42. Barefoot JC, Gronbaek M, Feaganes JR, et al. Alcoholic beverage preference, diet, and health habits in the UNC Alumni Heart Study. Am J Clin Nutr. 2002;76:466–472
  43. Ford AC, Forman D, Reynolds PD, et al. Ethnicity, gender, and socioeconomic status as risk factors for esophagitis and Barrett's esophagus. Am J Epidemiol. 2005;162:454–460
  44. Jansson C, Nordenstedt H, Johansson S, et al. Relation between gastroesophageal reflux symptoms and socioeconomic factors: a population-based study (the HUNT Study). Clin Gastroenterol Hepatol. 2007;5:1029–1034
  45. Morrison A. Screening in Chronic Disease. New York: Oxford University Press; 1992;
  46. Gordon N. Characteristics of adult members in Kaiser Permanente's Northern California Region as estimated from the 2005 Kaiser Permanente Adult Member Health Survey. Oakland CA: Kaiser Permanente Division of Research; 2008;http://www.dor.kaiser.org/dor/mhsnet/public/

 This article has an accompanying continuing medical education activity on page 1105. Learning Objective—At the end of this activity, the successful learner should be able to identify major known risk factors of Barrett's esophagus and esophageal adenocarcinoma.

 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by National Institutes of Health grants K08DK002697 and RO1 DK63616, and a Kaiser Permanente/Permanente Medical Group Community Benefits grant.

PII: S0016-5085(08)02073-8

doi: 10.1053/j.gastro.2008.11.042

Gastroenterology
Volume 136, Issue 3 , Pages 806-815 , March 2009

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