Gastroenterology
Volume 135, Issue 5 , Pages 1452-1454 , November 2008

Using Higher Risk Organs for Liver Transplantation: In Whom and at What Price?

  • Bilal Hameed
    • ,
  • John R. Lake

      Affiliations

    • Corresponding Author InformationAddress requests for reprints to John R. Lake, MD, Professor, University of Minnesota, Division of Gastroenterology & Hepatology, 420 Delaware Street SE MMC 36, Minneapolis, MN 55455. fax 612-625-5620

References 

  1. Organ Procurement and Transplantation Network. Homepage on the Internet. http://www.optn.org
  2. Malinchoc M, Kamath PS, Gordon FD, et al. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology. 2000;30:864
  3. Wiesner R, Edwards E, Freeman R, et al. United network for organ sharing liver disease severity score committee (Model for end-stage liver disease (MELD) and allocation of donor livers). Gastroenterology. 2003;124:91–96
  4. Saab S, Wang V, Ibrahim AB, et al. MELD score predicts 1-year patient survival post-orthotopic liver transplantation. Liver Transplantation. 2003;9:473–476
  5. 2006 Annual Report of the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1994–2006. Rockville, MD: Department of Health and Human Services, Health Resources and Services Administration, Healthcare Systems Bureau, Division of Transplantation; Richmond, VA: United Network for Organ Sharing; Ann Arbor, MI: University Renal Research and Education Association; 2006.
  6. Feng S, Goodrich NP, Bragg-Gresham JL, et al. Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant. 2006;6:783–789
  7. Volk ML, Lok AS, Pelltier SJ, et al. Impact of the model for end-stage liver disease allocation policy on the use of high-risk organs for liver transplantation. Gastroenterology. 2008;135:1568–1574
  8. Shafer TJ, Wagner D, Chessare J, et al. US organ donation breakthrough collaborative increases organ donation. Crit Care Nurs Q. 2008;31:190–210
  9. Freeman RB, Steffick DE, Guidinger MK, et al. Liver and intestine transplantation in the United States, 1997-2006. Am J Transplant. 2008;8:958–976
  10. Schaubel DE, Sima CS, Goodrich NP, et al. The survival benefit of deceased donor liver transplantation as a function of candidate disease severity and donor quality. Am J Transplant. 2008;8:419–425
  11. Maluf DG, Edwards EB, Kauffman HM. Utilization of extended donor criteria liver allograft: is the elevated risk of failure independent of the model for end-stage liver disease score of the recipient?. Transplantation. 2006;82:1653–1657
  12. Merion RM, Schaubel DE, Dykstra DM, et al. The survival benefit of liver transplantation. Am J Transplant. 2005;5:307–313
  13. Lucey MR, Brown KA, Everson GT, et al. Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases. Liver Transplant Surg. 1997;3:628–637
  14. Ioannou GN. Development and validation of a model predicting graft survival after liver transplantation. Liver Transpl. 2006;12:1594–1606
  15. Amin MG, Wolf MP, TenBrook JA, et al. Expanded criteria donor grafts for deceased donor liver transplantation under the MELD system: a decision analysis. Liver Transpl. 2004;10:1468–1475

 The authors disclose no conflicts.

PII: S0016-5085(08)01766-6

doi: 10.1053/j.gastro.2008.09.036

Gastroenterology
Volume 135, Issue 5 , Pages 1452-1454 , November 2008

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