Gastroenterology
Volume 135, Issue 6 , Pages 1945-1952 , December 2008

The Natural History of Serum Iron Indices for HFE C282Y Homozygosity Associated With Hereditary Hemochromatosis

  • Lyle C. Gurrin

      Affiliations

    • Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    • ,
  • Nicholas J. Osborne

      Affiliations

    • Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    • Murdoch Childrens Research Institute, Victoria, Australia
    • ,
  • Clare C. Constantine

      Affiliations

    • Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    • Department of Epidemiology University of California, Irvine, California
    • ,
  • Christine E. McLaren

      Affiliations

    • Department of Epidemiology University of California, Irvine, California
    • ,
  • Dallas R. English

      Affiliations

    • Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    • Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    • ,
  • Dorota M. Gertig

      Affiliations

    • Victorian Cervical Cytology Registry, Melbourne, Australia
    • ,
  • Martin B. Delatycki

      Affiliations

    • Murdoch Childrens Research Institute, Victoria, Australia
    • Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Victoria, Australia
    • ,
  • Melissa C. Southey

      Affiliations

    • Department of Pathology, The University of Melbourne, Melbourne, Australia
    • ,
  • John L. Hopper

      Affiliations

    • Centre for MEGA Epidemiology, School of Population Health, The University of Melbourne, Melbourne, Australia
    • ,
  • Graham G. Giles

      Affiliations

    • Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia
    • ,
  • Gregory J. Anderson

      Affiliations

    • Queensland Institute of Medical Research and the University of Queensland, Brisbane, Australia
    • ,
  • John K. Olynyk

      Affiliations

    • Department of Gastroenterology, Fremantle Hospital, Fremantle, Australia
    • School of Medicine and Pharmacology, University of Western Australia, Nedlands, Australia
    • Western Australian Institute of Medical Research, Perth, Australia
    • ,
  • Laurie W. Powell

      Affiliations

    • Queensland Institute of Medical Research and the University of Queensland, Brisbane, Australia
    • The University of Queensland and the Royal Brisbane and Women's Hospital, Brisbane, Australia
    • ,
  • Katrina J. Allen

      Affiliations

    • Murdoch Childrens Research Institute, Victoria, Australia
    • Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Victoria, Australia
    • Department of Gastroenterology, Royal Children's Hospital, Victoria, Australia
    • Corresponding Author InformationAddress requests for reprints to: Katie Allen, Associate Professor, Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Rd, Parkville, 3025, Victoria, Australia. fax: (61) 3 9345 6240
    • ,
  • HealthIron Study Investigators

Received 25 April 2008 ,Accepted 28 August 2008.

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 The HealthIron Study Investigators also include Melanie Bahlo (The Walter & Eliza Hall Institute for Medical Research, Melbourne, Australia), Amanda Nicoll (Royal Melbourne Hospital, Melbourne, Australia), Amy Nisselle (Murdoch Childrens Research Institute, Melbourne, Australia), and Chris Vulpe (University of California, Berkeley, California).

 The authors disclose the following: Supported by the National Institute of Diabetes, Digestive and Kidney Diseases (US) (1 RO1 DK061885-01 A2); National Health and Medical Research Council (NHMRC) (Australia) (project grant number 251668); by VicHealth and The Cancer Council Victoria for cohort recruitment; The Cancer Council Victoria and the NHMRC (program grant 209057, enabling grant 396414) for continuing follow-up; and by NHMRC Career Development Award (to L.C.G. and K.J.A), NHMRC Practitioner Fellowship (to M.B.D. and J.K.O), NHMRC Senior Research Fellowship (to M.C.S and G.J.A.), and NHMRC Australia Fellowship (to J.L.H.).

PII: S0016-5085(08)01666-1

doi: 10.1053/j.gastro.2008.08.056

Gastroenterology
Volume 135, Issue 6 , Pages 1945-1952 , December 2008

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