Gastroenterology
Volume 135, Issue 4 , Pages 1176-1184, October 2008

Randomized, Placebo-Controlled Trial of Pioglitazone in Nondiabetic Subjects With Nonalcoholic Steatohepatitis

  • Guruprasad P. Aithal

      Affiliations

    • University Hospitals NHS Trust, Nottingham, United Kingdom
    • Corresponding Author InformationAddress reprint requests to: Guruprasad P. Aithal, MD, PhD, Consultant Hepatobiliary Physician, D Floor, South Block, Queen's Medical Centre University Hospital, Derby Road, Nottingham NG72UH, United Kingdom. fax: +44 (0)115-9709012
    • ,
  • James A. Thomas

      Affiliations

    • University Hospitals NHS Trust, Nottingham, United Kingdom
    • ,
  • Philip V. Kaye

      Affiliations

    • University Hospitals NHS Trust, Nottingham, United Kingdom
    • ,
  • Adam Lawson

      Affiliations

    • University Hospitals NHS Trust, Nottingham, United Kingdom
    • ,
  • Stephen D. Ryder

      Affiliations

    • University Hospitals NHS Trust, Nottingham, United Kingdom
    • ,
  • Ian Spendlove

      Affiliations

    • University of Nottingham, Nottingham, United Kingdom
    • ,
  • Andrew S. Austin

      Affiliations

    • Derby City General Hospital, Derby, United Kingdom
    • ,
  • Jan G. Freeman

      Affiliations

    • Derby City General Hospital, Derby, United Kingdom
    • ,
  • Linda Morgan

      Affiliations

    • University of Nottingham, Nottingham, United Kingdom
    • ,
  • Jonathan Webber

      Affiliations

    • University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom

Received 12 May 2008; accepted 19 June 2008. published online 27 June 2008.

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 Takeda Pharmaceuticals UK provided the pioglitazone and placebo tablets for this investigator-initiated study. Jonathan Webber has received funding from Takeda, Novo, Sanofi-Aventis, and Pfizer to attend meetings. Investigator conflicts of interests were disclosed to study participants.

PII: S0016-5085(08)01101-3

doi:10.1053/j.gastro.2008.06.047

Gastroenterology
Volume 135, Issue 4 , Pages 1176-1184, October 2008

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