Gastroenterology
Volume 135, Issue 3 , Pages 917-925, September 2008

Ovalbumin-Protein σ1 M-Cell Targeting Facilitates Oral Tolerance With Reduction of Antigen-Specific CD4+ T Cells

  • Hideaki Suzuki

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Shinichi Sekine

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Kosuke Kataoka

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • Department of Preventive Dentistry, Institute of Health Biosciences, The University of Tokushima, Tokushima-City, Tokushima, Japan
    • ,
  • David W. Pascual

      Affiliations

    • Veterinary Molecular Biology, Montana State University, Bozeman, Montana
    • ,
  • Massimo Maddaloni

      Affiliations

    • Veterinary Molecular Biology, Montana State University, Bozeman, Montana
    • ,
  • Ryoki Kobayashi

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Keiko Fujihashi

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Haruo Kozono

      Affiliations

    • Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba, Japan
    • ,
  • Jerry R. McGhee

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • ,
  • Kohtaro Fujihashi

      Affiliations

    • The Immunobiology Vaccine Center, Departments of Pediatric Dentistry and Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama
    • Corresponding Author InformationAddress requests for reprints to: Kohtaro Fujihashi, The Department of Pediatric Dentistry, The Immunobiology Vaccine Center, The University of Alabama at Birmingham, 801A1 School of Dentistry Building, 1919 7th Avenue South, Birmingham, AL 35294-0007. fax: (205) 975-4431

Received 7 September 2007; accepted 8 May 2008. published online 16 May 2008.

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    •  Supported by grants from the US Public Health Service (AI 18958, DE 12242, AG 025873, and DE 13812).

     All authors declare that they have no conflict of interest to disclose.

    PII: S0016-5085(08)00857-3

    doi:10.1053/j.gastro.2008.05.037

    Gastroenterology
    Volume 135, Issue 3 , Pages 917-925, September 2008