Gastroenterology
Volume 135, Issue 2 , Pages 518-528.e3, August 2008

Toll-Like Receptor 5 Engagement Modulates Tumor Development and Growth in a Mouse Xenograft Model of Human Colon Cancer

  • Sang Hoon Rhee

      Affiliations

    • Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
  • ,
  • Eunok Im

      Affiliations

    • Division of Digestive Diseases, David Geffen School of Medicine, UCLA, Los Angeles, California
  • ,
  • Charalabos Pothoulakis

      Affiliations

    • Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
    • Corresponding Author InformationAddress requests for reprints to: Charalabos Pothoulakis, MD, MRL1519, 675 Charles E. Young Drive South, Inflammatory Bowel Disease Center, Division of Digestive Diseases, David Geffen School of Medicine, UCLA, Los Angeles, California 90095. fax: (310) 825-3542.

Received 20 December 2007; accepted 16 April 2008. published online 24 April 2008.

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 Supported by a Research Fellowship Award (to S.H.R.) from the “Crohn's and Colitis Foundation of America, Inc,” Young Clinical Scientific Award from Flight Attendant Medical Research Institute, Inc. (to S.H.R. and E.I.), and RO-1 DK072471 (to C.P.).

 Conflicts of interest: The authors declare that they have no competing financial interests.

 S.H.R. and C.P.'s current address is MRL1240, 675 Charles E. Young Drive South, Division of Digestive Diseases, David Geffen School of Medicine, UCLA, Los Angeles, California 90095.

PII: S0016-5085(08)00674-4

doi:10.1053/j.gastro.2008.04.022

Refers to article:

  • Guardians of the Gut: Newly Appreciated Role of Epithelial Toll-Like Receptors in Protecting the Intestine , 11 July 2008

    Matam Vijay-Kumar, Andrew T. Gewirtz
    Gastroenterology August 2008 (Vol. 135, Issue 2, Pages 351-354)

Gastroenterology
Volume 135, Issue 2 , Pages 518-528.e3, August 2008