Gastroenterology
Volume 134, Issue 1 , Pages 348-351 , January 2008

HCV, Iron, and Oxidative Stress: The New Choreography of Hepcidin

  • Debbie Trinder

      Affiliations

    • School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia
  • ,
  • Oyekoya T. Ayonrinde

      Affiliations

    • Department of Gastroenterology, Fremantle Hospital, Fremantle, Western Australia
  • ,
  • John K. Olynyk

      Affiliations

    • The Western Australian Institute of Medical Research, Perth, Western Australia
    • Corresponding Author InformationAddress requests for reprints to: John K. Olynyk, MD, School of Medicine and Pharmacology, University of Western Australia, Fremantle Hospital Campus, Fremantle, Western Australia.

  • Image Result

    Balance of factors such as HCV protein and alcohol induced ROS production, hemochromatosis mutations, iron and inflammation that influence hepcidin expression and regulate iron absorption, macrophage

    Balance of factors such as HCV protein and alcohol induced ROS production, hemochromatosis mutations, iron and inflammation that influence hepcidin expression and regulate iron absorption, macrophage recycling of iron and the level of iron in the liver.

PII: S0016-5085(07)02125-7

doi: 10.1053/j.gastro.2007.11.048

Gastroenterology
Volume 134, Issue 1 , Pages 348-351 , January 2008