Gastroenterology
Volume 134, Issue 1 , Pages 156-165.e1 , January 2008

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

  • Eoin P. Cummins

      Affiliations

    • UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
    • E.P.C., P.G.F., and C.T.T. contributed equally to this study.
  • ,
  • Fergal Seeballuck

      Affiliations

    • UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
    • Sigmoid Biotechnologies, Dublin, Ireland
  • ,
  • Stephen J. Keely

      Affiliations

    • Department of Molecular Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland
  • ,
  • Niamh E. Mangan

      Affiliations

    • Institute of Molecular Medicine, St James’s Hospital, Trinity College Dublin, Dublin, Ireland
  • ,
  • John J. Callanan

      Affiliations

    • UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
  • ,
  • Padraic G. Fallon

      Affiliations

    • Institute of Molecular Medicine, St James’s Hospital, Trinity College Dublin, Dublin, Ireland
    • E.P.C., P.G.F., and C.T.T. contributed equally to this study.
  • ,
  • Cormac T. Taylor

      Affiliations

    • UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland
    • E.P.C., P.G.F., and C.T.T. contributed equally to this study.
    • Corresponding Author InformationAddress requests for reprints to: Cormac T. Taylor, PhD, UCD Conway Institute, School of Medicine and Medical Science, College of Life Sciences, University College Dublin, Belfield, Dublin 4, Ireland. fax: (353) 1-716-6701.

Received 9 May 2007 ,Accepted 27 September 2007.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 30.00 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

 Supported by grants from the Science Foundation Ireland, the Wellcome Trust, the Health Research Board of Ireland, and the Irish Higher Education Authority Programme for Research in Third Level Institutions. We thank Brian Cloak for imaging expertise.

PII: S0016-5085(07)01811-2

doi: 10.1053/j.gastro.2007.10.012

Gastroenterology
Volume 134, Issue 1 , Pages 156-165.e1 , January 2008