Gastroenterology
Volume 133, Issue 3 , Pages 799-807.e1, September 2007

Natural History of Functional Gastrointestinal Disorders: A 12-year Longitudinal Population-Based Study

  • Smita L.S. Halder

      Affiliations

    • Dyspepsia Center, Enteric Neuroscience Program, Division of Gastroenterology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
    • S.L.S.H. is the recipient of an MRC Special Research Training Fellowship in Health Services & Health of the Public Research.
    • Dr. Halder’s current address is Department of Gastroenterology, Hope Hospital, University of Manchester, United Kingdom.
    • ,
  • G. Richard Locke III

      Affiliations

    • Dyspepsia Center, Enteric Neuroscience Program, Division of Gastroenterology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
    • Corresponding Author InformationAddress requests for reprints to: G. Richard Locke III, MD, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905. fax: (507) 538 7202.
    • ,
  • Cathy D. Schleck

      Affiliations

    • Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota
    • ,
  • Alan R. Zinsmeister

      Affiliations

    • Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota
    • ,
  • L. Joseph Melton III

      Affiliations

    • Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota
    • ,
  • Nicholas J. Talley

      Affiliations

    • Dyspepsia Center, Enteric Neuroscience Program, Division of Gastroenterology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
    • Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota

Received 21 July 2006; accepted 11 June 2007. published online 22 June 2007.

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 Supported in part by grants AGO9440 and AR30582 from the National Institutes of Health, US Public Health Service, and a grant from Novartis Pharmaceuticals.

 The authors wish to thank Carol Van Dyke for her assistance in mailing the surveys; Dixie Tesmer for her assistance with data entry; and Karen Kruger, Mary Jo Philo, and Sue Schlichter for their assistance in preparing the manuscript.

 Conflicts of Interest: N.J.T. is a consultant for the AGA; Cerebrio; Giaconda Ltd.; Interactive Forums, Inc.; JestaRx Group, Inc.; Johnson & Johnson Pharmaceutical R & D; Medscape from WebMD; Pfizer; Procter & Gamble; Strategic Consultants Intl; and Thervance, Inc and receives financial support from Novartis, Takeda, GlaxoSmithKline, Dynogen, and Tioga. G.R.L. is a consultant for Takeda and receives financial support from Novartis, Boehringer Ingelheim, and TAP.

PII: S0016-5085(07)01151-1

doi:10.1053/j.gastro.2007.06.010

Gastroenterology
Volume 133, Issue 3 , Pages 799-807.e1, September 2007

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