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Gastroenterology
Volume 133, Issue 2
, Pages 393-402
, August 2007
Risk of Colorectal Cancer in Patients Prescribed Statins, Nonsteroidal Anti-Inflammatory Drugs, and Cyclooxygenase-2 Inhibitors: Nested Case-Control Study
References
- . Colorectal cancer. Lancet. 2005;365:153–165
- . Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface (Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth). J Biol Chem. 1996;271:17453–17462
- . Stimulation of human breast cancer MCF-7 cells with estrogen prevents cell cycle arrest by HMG-CoA reductase inhibitors. Biochem Biophys Res Commun. 1996;220:864–870
- . Anti-carcinogenic activity of simvastatin during the promotion phase of radiation-induced mammary tumorigenesis of rats. Carcinogenesis. 1997;18:1723–1727
- . Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin. Cancer Res. 1991;51:3602–3609
- . Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. ClinCancer Res. 1999;5:2223–2229
- . Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels. JAMA. 1998;279:1349–1357
- . Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA. 2002;288:2998–3007
- . MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high risk individuals: a randomised placebo-controlled trial. Lancet. 2002;360:7–22
- . PROspective Study of Pravastatin in the Elderly at Risk (Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial). Lancet. 2002;360:1623–1630
- . Statins and cancer risk–a meta-analysis. JAMA. 2006;295:74–80
- . 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer. Arch Intern Med. 2000;160:2363–2368
- . Cancer risk among statin users: A population-based cohort study. Int J Cancer. 2005;114:643–647
- . Statins and the risk of lung, breast, and colorectal cancer in the elderly. Circulation. 2007;115:27–33
- . Cholesterol-lowering drugs and colorectal cancer incidence in a large United States cohort. J Natl Cancer Inst. 2006;98:69–72
- . Statins and risk of colorectal cancer. N Engl J Med. 2005;352:2184–2192
- . Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacological and clinical issues. J Natl Cancer Inst. 2002;94:252–266
- . Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs. Epidemiology. 2001;12:88–93
- . Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med. 2005;352:1092–1102
- . Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med. 2006;355:873–884
- Key Health Statistics from General Practice 1998: series MB6 (no 2). London, United Kingdom: Office for National Statistics; 2000;
- . Prevalence, care and outcomes for patients with diet controlled diabetes in general practice: cross sectional survey. Lancet. 2004;364:423–428
- . A comparison of research general practices and their patients with other practices--cross sectional survey in Trent. Br J Gen Pract. 2002;52:463–468
- . How useful are general practice databases for research? (Analysis of their accuracy and completeness in one research network). Health Informatics J. 2004;10:91–109
- . Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxgenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. BMJ. 2005;331:1310–1316
- . Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. BMJ. 2005;330:1366–1374
- . Effect of combinations of drugs on all cause mortality in patients with ischaemic heart disease: nested case-control analysis. BMJ. 2005;330:1059–1063
- . Calcium-channel blockers and risk of cancer. Lancet. 1997;349:525–528
- . Deprivation and cause specific morbidity: evidence from the Somerset and Avon survey of health. BMJ. 1996;312:287–292
- Cancer Statistics Registration 2003: series MB1 (no 34). London, United Kingdom: Office for National Statistics; 2005;
- . Long term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA. 2005;294:914–923
- . Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med. 2006;355:885–895
- . The risk of cancer in users of statins. J Clin Oncol. 2004;22:2388–2394
- . Statin use and risk of colorectal cancer. J Natl Cancer Inst. 2007;99:32–40
- . Accuracy of diagnosis of psychosis in general practice computer system. BMJ. 1993;307:32–34
- . Reducing DCO registrations through electronic matching of cancer registry data and routine hospital data. Br J Cancer. 2000;82:714–717
Supported by the University of Nottingham. This work was undertaken during the course of normal academic duties. The QResearch database undertakes other work for a variety of government organisations. This work was not commissioned or funded by any external organisation.
The study was initiated by JHC and designed by all the authors. The analysis was undertaken by YV and checked by JHC and CC. All authors contributed to the detailed analysis plan, interpretation of results, and drafting of the paper. YV and JHC are the guarantors of the study.
All authors declare that they have no conflict of interest to disclose.
PII: S0016-5085(07)01005-0
doi: 10.1053/j.gastro.2007.05.023
© 2007 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 133, Issue 2
, Pages 393-402
, August 2007

