Gastroenterology
Volume 133, Issue 2 , Pages 559-573, August 2007

Lamina Propria c-kit+ Immune Precursors Reside in Human Adult Intestine and Differentiate Into Natural Killer Cells

  • Hiroshi Chinen

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
    • Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
  • ,
  • Katsuyoshi Matsuoka

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Toshiro Sato

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Nobuhiko Kamada

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Susumu Okamoto

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Tadakazu Hisamatsu

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Taku Kobayashi

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Hirotoshi Hasegawa

      Affiliations

    • Department of Surgery, School of Medicine, Keio University, Tokyo, Japan
  • ,
  • Akira Sugita

      Affiliations

    • Department of Surgery, Yokohama Municipal Citizen’s Hospital, Yokohama, Japan
  • ,
  • Fukunori Kinjo

      Affiliations

    • Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
  • ,
  • Jiro Fujita

      Affiliations

    • Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan
  • ,
  • Toshifumi Hibi

      Affiliations

    • Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan
    • Corresponding Author InformationAddress requests for reprints to: Toshifumi Hibi, MD, PhD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Keio University, 35 Shinano-machi Shinjuku-ku, Tokyo 160-8585, Japan. fax: (81) 3-3357-6156.

Received 13 September 2006; accepted 26 April 2007. published online 22 May 2007.

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 Supported in part by grants-in-aid from the Japanese Ministry of Education, Culture and Science, the Japanese Ministry of Health, Labor and Welfare, Keio University and Keio Medical Foundation, Tokyo, Japan.

PII: S0016-5085(07)00999-7

doi:10.1053/j.gastro.2007.05.017

Gastroenterology
Volume 133, Issue 2 , Pages 559-573, August 2007