Gastroenterology
Volume 133, Issue 2 , Pages 507-516, August 2007

Functional Variants of the Central Bile Acid Sensor FXR Identified in Intrahepatic Cholestasis of Pregnancy

  • Saskia W.C. van Mil

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • Department of Metabolic and Endocrine Diseases, UMC Utrecht, Utrecht, The Netherlands
    • ,
  • Alexandra Milona

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Peter H. Dixon

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Roman Mullenbach

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Victoria L. Geenes

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Jenny Chambers

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Vasylyna Shevchuk

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Gudrun E. Moore

      Affiliations

    • Department of Clinical & Molecular Genetics, Institute of Child Health, University College London, London
    • ,
  • Frank Lammert

      Affiliations

    • Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany
    • ,
  • Anna G. Glantz

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital/East, Goteborg, Sweden
    • ,
  • Lars–Åke Mattsson

      Affiliations

    • Department of Obstetrics and Gynecology, Sahlgrenska University Hospital/East, Goteborg, Sweden
    • ,
  • John Whittaker

      Affiliations

    • Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, England
    • ,
  • Malcolm G. Parker

      Affiliations

    • Department of Molecular Endocrinology, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Roger White

      Affiliations

    • Department of Molecular Endocrinology, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • ,
  • Catherine Williamson

      Affiliations

    • Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Imperial College London, London, England
    • Corresponding Author InformationAddress requests for reprints to: Catherine Williamson, MD, Maternal and Fetal Disease Group, Institute of Reproductive and Developmental Biology, Division of Surgery, Oncology, Reproductive Biology and Anaesthetics, Faculty of Medicine, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0NN, England. fax: (44) 20 7594 2184.

Received 25 July 2006; accepted 3 May 2007. published online 23 May 2007.

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 Supported by Action Medical Research, Marie Curie Actions, the Institute of Obstetrics and Gynaecology Trust, the Lauren Page Trust, the Wellcome Trust, the German Research Council and the Department of Research and Development (FoU), Västra Götaland, Sweden.

PII: S0016-5085(07)00996-1

doi:10.1053/j.gastro.2007.05.015

Gastroenterology
Volume 133, Issue 2 , Pages 507-516, August 2007

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