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Gastroenterology
Volume 133, Issue 1
, Pages 24-33
, July 2007
The Fecal Microbiota of Irritable Bowel Syndrome Patients Differs Significantly From That of Healthy Subjects
References
- . Functional bowel disorders. Gastroenterology. 2006;130:1480–1491
- In: Drossman DA, Corazziari E, Talley NJ, Thompson WG, Whitehead WE editor. Rome II: the functional gastrointestinal disorders. 2nd ed. McLean, VA: Degnon Associates; 2000;
- . AGA technical review on irritable bowel syndrome. Gastroenterology. 2002;123:2108–2131
- . Effect of oral antibiotics on intestinal production of propionic acid. Arch Dis Child. 2000;82:169–172
- . Probiotics, antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in humans. Best Pract Res Clin Gastroenterol. 2003;17:775–783
- . Fecal microbial diversity in a strict vegetarian as determined by molecular analysis and cultivation. Microbiol Immunol. 2002;46:819–831
- . Obesity and gut flora. Nature. 2006;444:1009–1010
- . Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444:1022–1023
- . Proceedings: the faecal flora of patients with Crohn’s disease. Antonie van Leeuwenhoek. 1975;41:214–215
- . Alterations of the dominant faecal bacterial groups in patients with Crohn’s disease of the colon. Gut. 2003;52:237–242
- . Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut. 2004;53:685–693
- . Characterizing the composition of intestinal microflora as a prospective treatment target in infant allergic disease. FEMS Immunol Med Microbiol. 2001;32:1–7
- . Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects. J Allergy Clin Immunol. 2003;111:587–591
- . The fecal microbial population in the irritable bowel syndrome. Microbiologica. 1982;5:185–194
- . Abnormal colonic fermentation in irritable bowel syndrome. Lancet. 1998;352:1187–1189
- . Increased risk of irritable bowel syndrome after bacterial gastroenteritis: cohort study. BMJ (Clin Res Ed). 1999;318:565–566
- . Intestinal microecology and quality of life in irritable bowel syndrome patients. World J Gastroenterol. 2004;10:1802–1805
- . Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl Environ Microbiol. 1999;65:4799–4807
- . Human colonic biota studied by ribosomal DNA sequence analysis. Appl Environ Microbiol. 1996;62:2273–2278
- . Differential amplification of rRNA genes by polymerase chain reaction. Appl Environ Microbiol. 1992;58:3417–3418
- . DNA-based monitoring of total bacterial community structure in environmental samples. Mol Ecol. 1995;4:627–631
- . Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR. Am J Gastroenterol. 2005;100:373–382
- . Functional bowel disorders and functional abdominal pain. Gut. 1999;45(Suppl 2):II43–II47
- . Effective recovery of bacterial DNA and percent-guanine-plus-cytosine-based analysis of community structure in the gastrointestinal tract of broiler chickens. Appl Environ Microbiol. 1998;64:4084–4088
- . DNA probe method for the detection of specific microorganisms in the soil bacterial community. Appl Environ Microbiol. 1988;54:703–711
- . Dual staining of natural bacterioplankton with 4′,6-diamidino-2-phenylindole and fluorescent oligonucleotide probes targeting kingdom-level 16S rRNA sequences. Appl Environ Microbiol. 1992;58:2158–2163
- . Development of a membrane-array method for the detection of human intestinal bacteria in fecal samples. Mol Cell Probes. 2002;16:341–350
- . Isolation and direct complete nucleotide determination of entire genes (Characterization of a gene coding for 16S ribosomal RNA). Nucleic Acids Res. 1989;17:7843–7853
- . In: The Staden package, 1998 (Methods in molecular biology). Clifton, NJ: The Humana Press Inc., Totowa; 2000;p. 115–130132
- . Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 2003;31:3497–3500
- . Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness. Appl Environ Microbiol. 2005;71:1501–1506
- . Improved tools for biological sequence comparison. Proc Natl Acad Sci U S A. 1988;85:2444–2448
- . The Ribosomal Database Project (RDP-II): sequences and tools for high-throughput rRNA analysis. Nucleic Acids Res. 2005;33:D294–D296
- . Integration of microbial ecology and statistics: a test to compare gene libraries. Appl Environ Microbiol. 2004;70:5485–5492
- . Bayesian analysis of population structure based on linked molecular information. Math Biosci. 2007;205:19–31
- . The population frequencies of species and the estimation of population parameters. Biometrika. 1953;237–264
- . Multivariate observations. Mississauga, Canada: Wiley; 1984;
- . ARB: a software environment for sequence data. Nucleic Acids Res. 2004;32:1363–1371
- . Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set. Microbiology. 2002;148:257–266
- . Host-bacterial mutualism in the human intestine. Science. 2005;307:1915–1920
- . Culture-independent microbial community analysis reveals that inulin in the diet primarily affects previously unknown bacteria in the mouse cecum. Appl Environ Microbiol. 2002;68:4986–4995
- . Selective plating underestimates abundance and shows differential recovery of bifidobacterial species from human feces. Appl Environ Microbiol. 2003;69:5731–5735
- . Diversity of the human intestinal microbial flora. Science. 2005;308:1635–1638
- . Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell. 2006;124:837–848
- . Phylogenetic analysis of the human gut microbiota using 16S rDNA clone libraries and strictly anaerobic culture-based methods. Microbiol Immunol. 2002;46:535–548
- . An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444:1027–1131
- . Comparison of fecal microflora of elderly persons in rural and urban areas of Japan. Appl Environ Microbiol. 1989;55:1100–1105
- . Intestinal floras of populations that have a high risk of colon cancer. Appl Environ Microbiol. 1995;61:3202–3207
- . Irritable bowel syndrome and probiotics: from rationale to clinical use. Curr Opin Gastroenterol. 2005;21:697–701
- . A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6-month intervention. Aliment Pharmacol Ther. 2005;22:387–394
- . A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating. Neurogastroenterol Motil. 2005;17:687–696
- . Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome—a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol. 2005;43:213–222
- . Prevalence and temporal stability of selected clostridial groups in irritable bowel syndrome in relation to predominant faecal bacteria. J Med Microbiol. 2006;55:625–633
The authors have no conflicts of interest to disclose.Supported by the Finnish Funding Agency for Technology and Innovation (Tekes), Finnish Graduate School of Applied Biosciences.
PII: S0016-5085(07)00734-2
doi: 10.1053/j.gastro.2007.04.005
© 2007 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 133, Issue 1
, Pages 24-33
, July 2007

