Gastroenterology
Volume 132, Issue 5 , Pages 1925-1936 , May 2007

Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin

  • Stephen J. Polyak

      Affiliations

    • Department of Laboratory Medicine, University of Washington, Seattle, Washington
    • Department of Microbiology, University of Washington, Seattle, Washington
    • Department of Pathobiology, University of Washington, Seattle, Washington
    • S. J. P. is partially supported by NIH Grants R01 DK 62187 and U19 AI 66328 from NIDDK and NIAID, respectively.
    • Corresponding Author InformationAddress requests for reprints to: S. J. Polyak, PhD, University of Washington, Virology 359690, 325 9th Avenue, Seattle, Washington 98104-2499. fax: (206) 341-5203.
    • ,
  • Chihiro Morishima

      Affiliations

    • Department of Laboratory Medicine, University of Washington, Seattle, Washington
    • ,
  • Margaret C. Shuhart

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • ,
  • Chia C. Wang

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Washington
    • ,
  • Yanze Liu

      Affiliations

    • Department of Psychiatry, McLean General Hospital, Harvard Medical School, Boston, Massachusetts
    • Natural Pharmacia International Inc., Burlington, Massachusetts
    • ,
  • David Y.–W. Lee

      Affiliations

    • Department of Psychiatry, McLean General Hospital, Harvard Medical School, Boston, Massachusetts
    • D. Y. W.–L. is supported in part by NIH-STTR grant (R42-AT-00766) to Natural Pharmacia International Inc.

Received 7 November 2006 ,Accepted 8 February 2007.

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 The authors of this study have no conflicts of interest to disclose.

PII: S0016-5085(07)00395-2

doi: 10.1053/j.gastro.2007.02.038

Gastroenterology
Volume 132, Issue 5 , Pages 1925-1936 , May 2007

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