Gastroenterology
Volume 132, Issue 3 , Pages 905-912, March 2007

A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors

  • Georgina L. Hold

      Affiliations

    • Department of Medicine and Therapeutics, Aberdeen University, Aberdeen, Scotland
    • ,
  • Charles S. Rabkin

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland
    • ,
  • Wong–Ho Chow

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland
    • ,
  • Malcolm G. Smith

      Affiliations

    • Department of Medicine and Therapeutics, Aberdeen University, Aberdeen, Scotland
    • ,
  • Marilie D. Gammon

      Affiliations

    • Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina
    • ,
  • Harvey A. Risch

      Affiliations

    • Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Connecticut
    • ,
  • Thomas L. Vaughan

      Affiliations

    • Program in Epidemiology, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington
    • ,
  • Kenneth E.L. McColl

      Affiliations

    • Department of Medicine and Therapeutics, Glasgow University, Western Infirmary, Glasgow, UK
    • ,
  • Jolanta Lissowska

      Affiliations

    • Division of Cancer Epidemiology and Prevention, Cancer Centre and M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland
    • ,
  • Witold Zatonski

      Affiliations

    • Division of Cancer Epidemiology and Prevention, Cancer Centre and M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland
    • ,
  • Janet B. Schoenberg

      Affiliations

    • Applied Cancer Epidemiology Program, New Jersey Department of Health and Senior Services, Trenton, New Jersey
    • ,
  • William J. Blot

      Affiliations

    • International Epidemiology Institute, Rockville, Maryland
    • ,
  • N. Ashley G. Mowat

      Affiliations

    • Department of Medicine and Therapeutics, Aberdeen University, Aberdeen, Scotland
    • ,
  • Joseph F. Fraumeni Jr

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland
    • ,
  • Emad M. El–Omar

      Affiliations

    • Department of Medicine and Therapeutics, Aberdeen University, Aberdeen, Scotland
    • Corresponding Author InformationAddress requests for reprints to: Professor Emad M. El-Omar, MD, Department of Medicine and Therapeutics, Aberdeen University, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD, Scotland. fax: (44) 1224-555766.

Received 16 January 2006; accepted 30 November 2006. published online 19 December 2006.

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 Supported by a grant from Cancer Research UK (C8969/A3868), and by the Intramural Research Program of the National Cancer Institute, National Institutes of Health.

PII: S0016-5085(06)02676-X

doi:10.1053/j.gastro.2006.12.026

Gastroenterology
Volume 132, Issue 3 , Pages 905-912, March 2007

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