Gastroenterology
Volume 132, Issue 3 , Pages 938-943 , March 2007

Growth Hormone Reverses Nonalcoholic Steatohepatitis in a Patient With Adult Growth Hormone Deficiency

  • Yutaka Takahashi

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • Corresponding Author InformationAddress requests for reprints to: Yutaka Takahashi, MD, PhD, Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, 7-5-2, Kusunoki-cho, Chuo-ku, Kobe 650-0017 Japan. fax: (81) 78-382-5899.
    • ,
  • Keiji Iida

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Kentaro Takahashi

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Shiro Yoshioka

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Hidenori Fukuoka

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Ryoko Takeno

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Mari Imanaka

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Hitoshi Nishizawa

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Michiko Takahashi

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Yasushi Seo

      Affiliations

    • Division of Diabetes, Digestive, and Kidney Diseases, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Yoshitake Hayashi

      Affiliations

    • Division of Molecular Medicine & Medical Genetics, International Center for Medical Research and Treatment, Department of Biomedical Informatics, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Takuma Kondo

      Affiliations

    • Kondo Pediatric Clinic, Osaka, Japan
    • ,
  • Yasuhiko Okimura

      Affiliations

    • Department of Basic Allied Medicine, Kobe University School of Medicine, Kobe, Japan
    • ,
  • Hidesuke Kaji

      Affiliations

    • College of Nursing Art and Culture, Akashi, Japan
    • ,
  • Riko Kitazawa

      Affiliations

    • Division of Molecular Pathology, Department of Biomedical Informatics, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Sohei Kitazawa

      Affiliations

    • Division of Molecular Pathology, Department of Biomedical Informatics, Kobe University Graduate School of Medicine, Kobe, Japan
    • ,
  • Kazuo Chihara

      Affiliations

    • Division of Endocrinology/Metabolism, Neurology, and Hematology/Oncology, Department of Clinical Molecular Medicine, Kobe University Graduate School of Medicine, Kobe, Japan

Received 17 October 2006 ,Accepted 27 November 2006.

References 

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  20. Sesmilo G, Miller KK, Hayden D, Klibanski A. Inflammatory cardiovascular risk markers in women with hypopituitarism. J Clin Endocrinol Metab. 2001;86:5774–5781
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  27. Lonardo A, Loria P, Leonardi F, Ganazzi D, Carulli N. Growth hormone plasma levels in nonalcoholic fatty liver disease. Am J Gastroenterol. 2002;97:1071–1972

 Supported in part by a Grant-in-Aid for Scientific Research from the Japanese Ministry of Education Science, Sports, and Culture; grants from the Foundation for Growth Science, Novo Nordisk Growth and Development Foundation; and a grant for the 21st Century COE Program, “Center of Excellence for Signal Transduction Disease: Diabetes Mellitus as Model” from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

PII: S0016-5085(06)02674-6

doi: 10.1053/j.gastro.2006.12.024

Gastroenterology
Volume 132, Issue 3 , Pages 938-943 , March 2007

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