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Gastroenterology
Volume 132, Issue 2
, Pages 543-550
, February 2007
Identification of a Hepatitis B Virus S Gene Mutant in Lamivudine-Treated Patients Experiencing HBsAg Seroclearance
References
- . Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat. 2004;11:97–107
- . The development of cirrhosis in patients with chronic type B hepatitis: a prospective study. Hepatology. 1988;8:493–496
- . Natural history and prognostic factors for chronic hepatitis type B. Gut. 1991;32:294–298
- . Natural course after the development of cirrhosis in patients with chronic type B hepatitis: a prospective study. Liver. 1989;9:235–241
- . Hepatitis B virus: the major etiology of hepatocellular carcinoma. Cancer. 1988;61:1942–1956
- . Biochemical pharmacology of (+)- and (−)-2’,3’-dideoxy-3’-thiacytidine as anti-hepatitis B virus agents. J Biol Chem. 1992;267:22414–22420
- . Inhibition of the replication of hepatitis B virus in vitro by 2’,3’-dideoxy-3’-thiacytidine and related analogues. Proc Natl Acad Sci U S A. 1991;88:8495–8499
- . A one-year trial of lamivudine for chronic hepatitis B. N Engl J Med. 1998;339:61–68
- . A preliminary trial of lamivudine for chronic hepatitis B infection. N Engl J Med. 1995;333:1657–1661
- . Short-term lamivudine therapy in patients with chronic hepatitis B. Intervirology. 2003;46:362–366
- . Lamivudine therapy of WHV-infected woodchucks. Virology. 1998;245:18–32
- . Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus. J Virol. 1997;71:9392–9399
- . Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Gastroenterology. 2000;119:172–180
- . Therapy of chronic hepatitis B: current challenges and opportunities. J Viral Hepat. 2002;9:393–399
- . Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology. 1996;24:714–717
- . Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy. Hepatology. 1999;30:567–572
- . Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy. Hepatology. 2000;31:1318–1326
- . Management of antiviral resistance in patients with chronic hepatitis B. Antivir Ther. 2004;9:679–693
- . Vaccine-induced escape mutant of hepatitis B virus. Lancet. 1990;336:325–329
- . Surface gene variation of HBV: scientific and medical relevance. Viral Hepatitis Rev. 1997;3:5–16
- . HBsAg seroclearance in Chinese patients receiving lamividine therapy for chronic hepatitis B virus infection. J Clin Microbiol. 2004;42:4882–4884
- . Determinants for sustained HBeAg response to lamivudine therapy. Hepatology. 2003;38:1267–1273
- . Quantitative assessment of hepatitis C virus RNA by polymerase chain reaction and a digoxigenin detection system: comparison with branched DNA assay. J Virol Methods. 1997;65:219–226
- . Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B. Hepatology. 2002;35:1522–1527
- . Prognosis following spontaneous HBsAg seroclearance in chronic hepatitis B patients with or without concurrent infection. Gastroenterology. 2002;123:1084–1989
- . Genetic variability of the S gene of hepatitis B virus: clinical and diagnostic impact. J Clin Virol. 2005;32:102–112
- . Molecular and serological evaluation of surface antigen negative hepatitis B virus infection in blood donors from Venezuela. J Med Virol. 2004;73:200–207
- . Occult hepatitis B virus infection in a North American community-based population. J Hepatol. 2005;42:480–485
- . Loss of the common “a” determinant of hepatitis B surface antigen by a vaccine-induced escape mutant. J Clin Invest. 1992;90:2543–2547
- . Fulminant reactivation of hepatitis B due to envelope protein mutant that escaped detection by monoclonal HBsAg ELISA. Lancet. 1995;345:1406–1407
- . A molecular analysis of viral persistence in surface antigen-negative chronic hepatitis B. Hepatology. 1996;23:389–395
- . Effect of variation in the common “a” determinant on the antigenicity of hepatitis B surface antigen. J Med Virol. 2000;60:113–121
- . Identification of a novel pre-S2 mutation in a subgroup of chronic carriers with spontaneous clearance of hepatitis B virus surface antigen. J Gastroenterol Hepatol. 2003;18:1129–1138
- . Point mutation in the S gene of hepatitis B virus for a d/y or w/r subtypic change in two blood donors carrying a surface antigen of compound subtype adyr or adwr. J Virol. 1987;61:3030–3034
- . A unique insertion in the S gene of surface antigen-negative hepatitis B virus Chinese carriers. Hepatology. 1995;21:273–278
- . Emergence of an S gene mutant during thymosin α 1 therapy in a patient with chronic hepatitis B. J Infect Dis. 1998;178:866–869
Supported by grants from Chang Gung Medical Research Program (CMRP34032 to the Hepatoma Research Team).
PII: S0016-5085(06)02559-5
doi: 10.1053/j.gastro.2006.12.001
© 2007 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 132, Issue 2
, Pages 543-550
, February 2007

