Gastroenterology
Volume 132, Issue 1 , Pages 261-271, January 2007

Gastrointestinal Safety and Anti-Inflammatory Effects of a Hydrogen Sulfide–Releasing Diclofenac Derivative in the Rat

  • John L. Wallace

      Affiliations

    • Inflammation Research Network, University of Calgary, Calgary, Alberta, Canada
    • Corresponding Author InformationAddress requests for reprints to: John L. Wallace, PhD, Department of Pharmacology and Therapeutics, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, T2N 4N1, Canada. fax: (403) 270-3353.
  • ,
  • Giuseppe Caliendo

      Affiliations

    • Department of Medicinal Chemistry, University of Naples, Naples, Italy
  • ,
  • Vincenzo Santagada

      Affiliations

    • Department of Medicinal Chemistry, University of Naples, Naples, Italy
  • ,
  • Giuseppe Cirino

      Affiliations

    • Department of Experimental Pharmacology, University of Naples, Naples, Italy
  • ,
  • Stefano Fiorucci

      Affiliations

    • Inflammation Research Network, University of Calgary, Calgary, Alberta, Canada
    • Department of Gastroenterology and Hepatology, University of Perugia, Perugia, Italy

Received 13 August 2006; accepted 28 September 2006. published online 06 December 2006.

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 Supported by a grant from the Canadian Institutes of Health Research. J.L.W. holds a Canada Research Chair and is supported by an Alberta Heritage Foundation for Medical Research Senior Scientist Award.

 All authors of this paper hold shares in Antibe Therapeutics Inc.

PII: S0016-5085(06)02523-6

doi:10.1053/j.gastro.2006.11.042

Gastroenterology
Volume 132, Issue 1 , Pages 261-271, January 2007