Gastroenterology
Volume 132, Issue 1 , Pages 52-65 , January 2007

Adalimumab for Maintenance of Clinical Response and Remission in Patients With Crohn’s Disease: The CHARM Trial

  • Jean–Frédéric Colombel

      Affiliations

    • Department of Hepatogastroenterology, Hôpital Claude Huriez, Centre Hospitalier Universitaire de Lille, Lille, France
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
    • Corresponding Author InformationAddress requests for reprints to: Jean-Frédéric Colombel, MD, Hôpital Claude Huriez, Centre Hospitalier Universitaire de Lille, Rue Michel Polonovski, Lille, France 59037. fax: (33) 3-20-44-47-13.
  • ,
  • William J. Sandborn

      Affiliations

    • Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Paul Rutgeerts

      Affiliations

    • Department of Gastro-Enterologie, University Hospital of Gasthuisberg, Leuven, Belgium
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Robert Enns

      Affiliations

    • Department of Medicine, St. Paul’s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Stephen B. Hanauer

      Affiliations

    • Section of Gastroenterology, University of Chicago, Chicago, Illinois
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Remo Panaccione

      Affiliations

    • Department of Medicine, Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Stefan Schreiber

      Affiliations

    • Department of General Internal Medicine and Institute for Clinical Molecular Biology, Christian-Albrechts University, Kiel, Germany
    • Jean-Frédéric Colombel, William Sandborn, Paul Rutgeerts, Robert Enns, Stephen Hanauer, Remo Panaccione, and Stefen Schreiber have served as consultants for Abbott Laboratories and have participated in continuing medical education events supported by unrestricted educational grants from Abbott Laboratories.
  • ,
  • Dan Byczkowski

      Affiliations

    • Department of Immunology Development, Abbott Laboratories, Parsippany, New Jersey
    • Dan Byczkowski, Ju Li, Jeffrey Kent, and Paul Pollack are employees of Abbott Laboratories.
  • ,
  • Ju Li

      Affiliations

    • Department of Biostatistics and Data Management, Abbott Laboratories, Abbott Park, Illinois
    • Dan Byczkowski, Ju Li, Jeffrey Kent, and Paul Pollack are employees of Abbott Laboratories.
  • ,
  • Jeffrey D. Kent

      Affiliations

    • Department of Immunology Development, Abbott Laboratories, Parsippany, New Jersey
    • Dan Byczkowski, Ju Li, Jeffrey Kent, and Paul Pollack are employees of Abbott Laboratories.
  • ,
  • Paul F. Pollack

      Affiliations

    • Department of Immunology Development, Abbott Laboratories, Parsippany, New Jersey
    • Dan Byczkowski, Ju Li, Jeffrey Kent, and Paul Pollack are employees of Abbott Laboratories.

Received 11 August 2006 ,Accepted 28 September 2006.

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 Supported by a research grant from Abbott Laboratories (Abbott Park, IL).A list of the CHARM study investigators and sites appears in Appendix 1.

PII: S0016-5085(06)02522-4

doi: 10.1053/j.gastro.2006.11.041

Gastroenterology
Volume 132, Issue 1 , Pages 52-65 , January 2007