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Gastroenterology
Volume 132, Issue 2
, Pages 562-575
, February 2007
Soluble Proteins Produced by Probiotic Bacteria Regulate Intestinal Epithelial Cell Survival and Growth
References
- . Mucosal immunology and mechanisms of gastrointestinal inflammation. In: Feldman M, Friedman LS, Sleisenger MH editor. 7th ed.. Sleisenger & Fordtran’s gastrointestinal and liver disease: pathophysiology, diagnosis, management. Volume I:Philadelphia: Saunders; 2002;p. 21–51
- . HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation. Gastroenterology. 2005;129:609–625
- . Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis. Gastroenterology. 2005;128:975–986
- . Epidermal growth factor partially restores colonic ion transport responses in mouse models of chronic colitis. Gastroenterology. 2005;129:591–608
- . Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis. N Engl J Med. 2003;349:350–357
- . TNF-α neutralization ameliorates the severity of murine Crohn’s-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proc Natl Acad Sci U S A. 2003;100:8366–8371
- . Down-regulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumor necrosis factor α antibody treatment. Gut. 2004;53:1295–1302
- . Commensal bacteria in the gut: learning who our friends are. Curr Opin Gastroenterol. 2004;20:565–571
- . Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics. Gastroenterology. 2004;126:1620–1633
- . Probiotics: Growth-promoting factors produced by microorganisms. Science. 1965;147:747–748
- . Treatment of ulcerative colitis using fecal bacteriotherapy. J Clin Gastroenterol. 2003;37:42–47
- . Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment. Gut. 2003;52:370–376
- . Once daily high dose probiotic therapy (VSL#3) for maintaining remission in recurrent or refractory pouchitis. Gut. 2004;53:108–114
- . Lactobacillus GG in inducing and maintaining remission of Crohn’s disease. BMC Gastroenterol. 2004;4:5
- . Live probiotics protect intestinal epithelial cells from the effects of infection with enteroinvasive Escherichia coli (EIEC). Gut. 2003;52:988–997
- . Probiotics and commensals reverse TNF-α- and IFN-γ-induced dysfunction in human intestinal epithelial cells. Gastroenterology. 2006;130:731–746
- . Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut. 2003;52:827–833
- . Functional modulation of enterocytes by gram-positive and gram-negative microorganisms. Am J Physiol Gastrointest Liver Physiol. 2004;286:G613–G626
- . Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells. J Biol Chem. 2002;277:50959–50965
- . The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest. 2005;115:2618–2624
- . Structure, regulation and function of PKB/AKT—a major therapeutic target. Biochim Biophys Acta. 2004;1697:3–16
- . Soluble factors from Lactobacillus GG activate MAPKs and induce cytoprotective heat shock proteins in intestinal epithelial cells. Am J Physiol Cell Physiol. 2006;290:C1018–C1030
- . Production of human tumor necrosis factor α, interleukin-6, and interleukin-10 is induced by lactic acid bacteria. Infect Immun. 1996;64:5403–5405
- . Kinase suppressor of Ras protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest. 2004;114:1272–1280
- . Kinase suppressor of Ras determines survival of intestinal cells exposed to tumor necrosis factor. Cancer Res. 2001;61:8668–8675
- . Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry. 1998;31:1–9
- . Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. Mol Cell Biol. 2003;23:4511–4521
- . Probiotic bacteria stimulate gut epithelial cell proliferation in rat. Dig Dis Sci. 1999;44:2119–2123
- . Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut. 2003;52:1472–1478
- . Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells. J Immunol. 2006;176:1228–1237
- . Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017), and Bifidobacterium lactis (HN019). Br J Nutr. 2000;83:167–176
- . A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn’s disease. Inflamm Bowel Dis. 2005;11:833–839
- . Lactobacillus sepsis associated with probiotic therapy. Pediatrics. 2005;115:178–181
- . Good adhesion properties of probiotics: a potential risk for bacteremia?. FEMS Immunol Med Microbiol. 2001;31:35–39
- . Molecular analysis of commensal host-microbial relationships in the intestine. Science. 2001;291:881–884
- . A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science. 2003;299:2074–2076
- . Probiotics in inflammatory bowel disease: possible mechanisms of action. Curr Opin Gastroenterol. 2005;21:426–430
- . Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria. Science. 2004;303:1662–1665
- . Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor. J Clin Invest. 2005;115:2855–2861
- . The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt. J Biol Chem. 2005;280:9058–9064
- . Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-g and RelA (Epub December 21, 2003). Nat Immunol. 2004;5:104–112
- . Molecular aspects of intestinal epithelial cell-bacterial interactions that determine the development of intestinal inflammation. Inflamm Bowel Dis. 2004;10:159–168
Supported by NIH grants DK 065744 (to F.Y.), DK56008 (to D.B.P.), and DK58404 (Vanderbilt University Digestive Disease Research Center); Atticus Trust; Vanderbilt University Medical Center Imaging Core Research Laboratory grant (CA-68485); and the Department of Veterans Affairs.
PII: S0016-5085(06)02477-2
doi: 10.1053/j.gastro.2006.11.022
© 2007 AGA Institute. Published by Elsevier Inc. All rights reserved.
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Gastroenterology
Volume 132, Issue 2
, Pages 562-575
, February 2007

