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Gastroenterology
Volume 131, Issue 5
, Pages 1631-1634
, November 2006
The Serrated Polyp Comes of Age
References
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- . Mixed hyperplastic adenomatous polyps/serrated adenomas (A distinct form of colorectal neoplasia). Am J Surg Pathol. 1990;14:524–537
- . DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?. J Clin Pathol. 1999;52:5–9
- . Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol. 2004;28:423–434
- . Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas. J Natl Cancer Inst. 2001;93:1307–1313
- . Hyperplastic-like colon polyps that preceded microsatellite-unstable adenocarcinomas. Am J Clin Pathol. 2003;119:778–796
- . BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum. Gut. 2004;53:1137–1144
- . BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004;28:1452–1459
- . Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a “fusion” pathway to colorectal cancer. Histopathology. 2006;49:121–131
- . Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature. 2002;418:934
- . Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas. Int J Cancer. 2004;108:237–242
- . BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors. Cancer. 2005;104:952–961
- . BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res. 2003;63:5209–5212
- . BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer. Clin Cancer Res. 2004;10:191–195
- . High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy. Gastroenterology. 2006;131
- . Demographic and pathological characteristics of serrated polyps of colorectum. Histopathology. 2005;47:32–40
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PII: S0016-5085(06)02203-7
doi: 10.1053/j.gastro.2006.09.035
© 2006 AGA Institute. Published by Elsevier Inc. All rights reserved.
« Previous
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Gastroenterology
Volume 131, Issue 5
, Pages 1631-1634
, November 2006

