Gastroenterology
Volume 130, Issue 4 , Pages 1324-1332 , April 2006

Developmental Characteristics of Adapting Mouse Small Intestine Crypt Cells

  • Christopher R. Erwin

      Affiliations

    • Division of Pediatric and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
    • Corresponding Author InformationAddress requests for reprints to: Christopher R. Erwin, PhD, Division of Pediatric and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229.fax: (513) 636-2423.
    • ,
  • Marcus D. Jarboe

      Affiliations

    • Division of Pediatric and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
    • ,
  • Maureen A. Sartor

      Affiliations

    • Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Mario Medvedovic

      Affiliations

    • Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio
    • ,
  • Keith F. Stringer

      Affiliations

    • Department of Pathology and Laboratory Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
    • ,
  • Brad W. Warner

      Affiliations

    • Division of Pediatric and Thoracic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
    • ,
  • Michael D. Bates

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
    • Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA

Received 24 March 2005 ,Accepted 30 November 2005.

References 

  1. Williamson RC . Intestinal adaptation (first of two parts). Structural, functional and cytokinetic changes . N Engl J Med . 1978;298:1393–1402
  2. Williamson RC . Intestinal adaptation (second of two parts). Mechanisms of control . N Engl J Med . 1978;298:1444–1450
  3. Dauca M, Bouziges F, Colin S, Kedinger M, Keller MK, Schilt J, et al. Development of the vertebrate small intestine and mechanisms of cell differentiation . Int J Dev Biol . 1990;34:205–218
  4. Koldovsky O , Dobiasova M , Hahn P , Kolinska J , Kraml J , Pacha J . Development of gastrointestinal functions . Physiol Res . 1995;44:341–348
  5. Botsios DS , Vasiliadis KD . Factors enhancing intestinal adaptation after bowel compensation . Dig Dis . 2003;21:228–236
  6. Erwin CR , Falcone RA , Stern LE , Kemp CJ , Warner BW . Analysis of intestinal adaptation gene expression by cDNA expression arrays . JPEN J Parenter Enteral Nutr . 2000;24:311–316
  7. Stern LE, Erwin CR, Falcone RA, Huang FS, Kemp CJ, Williams JL, et al. cDNA microarray analysis of adapting bowel after intestinal resection . J Pediatr Surg . 2001;36:190–195
  8. Wildhaber BE , Yang H , Coran AG , Teitelbaum DH . Gene alteration of intestinal intraepithelial lymphocytes in response to massive small bowel resection . Pediatr Surg Int . 2003;19:310–315
  9. Marshman E , Booth C , Potten CS . The intestinal epithelial stem cell . Bioessays . 2002;24:91–98
  10. Todd R , Margolin DH . Challenges of single-cell diagnostics (analysis of gene expression) . Trends Mol Med . 2002;8:254–257
  11. Todd R , Lingen MW , Kuo WP . Gene expression profiling using laser capture microdissection . Expert Rev Mol Diagn . 2002;2:497–507
  12. Helmrath MA , VanderKolk WE , Can G , Erwin CR , Warner BW . Intestinal adaptation following massive small bowel resection in the mouse . J Am Coll Surg . 1996;183:441–449
  13. Bates MD, Erwin CR, Sanford LP, Wiginton D, Bezerra JA, Schatzman LC, et al. Novel genes and functional relationships in the adult mouse gastrointestinal tract identified by microarray analysis . Gastroenterology . 2002;122:1467–1482
  14. Knott AW , Erwin CR , Profitt SA , Juno RJ , Warner BW . Localization of postresection EGF receptor expression using laser capture microdissection . J Pediatr Surg . 2003;38:440–445
  15. Stappenbeck TS , Mills JC , Gordon JI . Molecular features of adult mouse small intestinal epithelial progenitors . Proc Natl Acad Sci U S A . 2003;100:1004–1009
  16. Nomura S, Baxter T, Yamaguchi H, Leys C, Vartapetian AB, Fox JG, et al. Spasmolytic polypeptide expressing metaplasia to preneoplasia in H. felis-infected mice . Gastroenterology . 2004;127:582–594
  17. Helmrath MA , Shin CE , Erwin CR , Warner BW . The EGF/EGF-receptor axis modulates enterocyte apoptosis during intestinal adaptation . J Surg Res . 1998;77:17–22
  18. Zhang J , Xu M , Aronow B . Expression profiles of 109 apoptosis pathway-related genes in 82 mouse tissues and experimental conditions . Biochem Biophys Res Commun . 2002;297:537–544
  19. Quaroni A . Fetal characteristics of small intestinal crypt cells . Proc Natl Acad Sci U S A . 1986;83:1723–1727
  20. Jegga AG, Sherwood SP, Carman JW, Pinski AT, Phillips JL, Pestian JP, et al. Detection and visualization of compositionally similar cis-regulatory element clusters in orthologous and coordinately controlled genes . Genome Res . 2002;12:1408–1417
  21. Parks CL , Shenk T . The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Sp1 . J Biol Chem . 1996;271:4417–4430
  22. Kadonaga JT , Carner KR , Masiarz FR , Tjian R . Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain . Cell . 1987;51:1079–1090
  23. Koritschoner NP , Bocco JL , Panzetta-Dutari GM , Dumur CI , Flury A , Patrito LC . A novel human zinc finger protein that interacts with the core promoter element of a TATA box-less gene . J Biol Chem . 1997;272:9573–9580

 Supported in part by National Institutes of Health grants DK53234 and DK59288 (to B.W.W.) as well as DK02791 and DK61219 (to M.D.B.).

PII: S0016-5085(06)00281-2

doi: 10.1053/j.gastro.2006.02.019

Gastroenterology
Volume 130, Issue 4 , Pages 1324-1332 , April 2006

Article Tools

* Image Usage & Resolution