Gastroenterology
Volume 130, Issue 3 , Pages 657-664 , March 2006

Biofeedback Is Superior to Laxatives for Normal Transit Constipation Due to Pelvic Floor Dyssynergia

  • Giuseppe Chiarioni

      Affiliations

    • Gastrointestinal Rehabilitation Division, Valeggio sul Mincio Hospital, Azienda Ospedaliera and University of Verona, Verona, Italy
    • Corresponding Author InformationAddress requests for reprints to: Giuseppe Chiarioni, MD, Divisione di Riabilitazione Gastroenterologica dell’Università di Verona, Azienda Ospedaliera di Verona, Centro Ospedaliero Clinicizzato, 37067 Valeggio sul Mincio (VR), Italy; fax: (39) 04579 50188.
    • ,
  • William E. Whitehead

      Affiliations

    • UNC Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    • ,
  • Vincenzo Pezza

      Affiliations

    • II Surgical Division, Arcispedale S. Maria Nuova, Azienda Ospedaliera, Reggio Emilia, Italy
    • ,
  • Antonio Morelli

      Affiliations

    • Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, Azienda Ospedaliera and University of Perugia, Perugia, Italy
    • ,
  • Gabrio Bassotti

      Affiliations

    • Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, Azienda Ospedaliera and University of Perugia, Perugia, Italy

Received 30 August 2005 ,Accepted 9 November 2005.

References 

  1. Lembo A , Camilleri M . Chronic constipation . N Engl J Med . 2003;349:1360–1368
  2. Whitehead WE , Wald A , Diamant NE , Enck P , Pemberton JH , Rao SS . Functional disorders of the anus and rectum . GUT . 1999;45(Suppl 2):II55–II59
  3. Heymen S , Jones KR , Scarlett Y , Whitehead WE . Biofeedback treatment of constipation (a critical review) . Dis Colon Rectum . 2003;46:1208–1217
  4. Thompson WG , Longstreth GF , Drossman DA , Heaton KW , Irvine EJ , Muller-Lissner SA . Functional bowel disorders and functional abdominal pain . Gut . 1999;45:43–47
  5. Chiarioni G , Salandini L , Whitehead WE . Biofeedback benefits only patients with outlet dysfunction, not patients with isolated slow transit constipation . Gastroenterology . 2005;129:86–97
  6. Hinton JM , Lennard-Jones JE , Young AC . A new method for studying gut transit times using radioopaque markers . Gut . 1969;10:842–847
  7. Scarlett YV . Anorectal manometry and biofeedback . In:  Drossman DA ,  Shaheen NJ ,  Grimm IS editor. Handbook of gastroenterologic procedures . 4th ed.. Philadelphia, PA: Lippincott Williams & Wilkins; 2005;p. 341–348
  8. Wald A , Chandra R , Gabel S , Chiponis D . Evaluation of biofeedback in childhood encopresis . J Pediatr Gastroenterol Nutr . 1987;6:554–558
  9. van der Plas RN, Benninga MA, Buller HA, Bossuyt PM, Akkermans LM, Redekop WK, et al. Biofeedback training in treatment of childhood constipation (a randomized controlled study) . Lancet . 1996;348:776–780
  10. van der Plas RN , Benninga MA , Redekop WK , Taminiau JA , Buller HA . Randomized trial of biofeedback training for encopresis . Arch Dis Child . 1996;75:367–374
  11. Nolan T , Catto-Smith T , Coffey C , Wells J . Randomized controlled trial of biofeedback training in persistent encopresis with anismus . Arch Dis Child . 1998;79:131–135
  12. Heymen S , Scarlett Y , Jones K , Drossman D , Ringel Y , Whitehead WE . Randomized controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation . Gastroenterology . 2005;128:A266
  13. Rao SS, Kinkade KJ, Schulze KS, Nygaard II, Brown KE, Stumbo PI, et al. Biofeedback therapy (bt) for dyssynergic constipation—randomized controlled trial . Gastroenterology . 2005;128:A269
  14. Chaussade S , Minic M . Comparison of efficacy and safety of two doses of two different polyethylene glycol-based laxatives in the treatment of constipation . Aliment Pharmacol Ther . 2003;17:165–172
  15. Corazziari E, Badiali D, Bazzocchi G, Bassotti G, Roselli P, Mastropaolo G, et al. Long-term efficacy, safety, and tolerability of low daily doses of isosmotic polyethylene glycol electrolyte balanced solution (PMF-100) in the treatment of functional chronic constipation . Gut . 2000;46:522–526

 Supported by grants RO1 DK57048 and R24 DK67674.

PII: S0016-5085(05)02274-2

doi: 10.1053/j.gastro.2005.11.014

Gastroenterology
Volume 130, Issue 3 , Pages 657-664 , March 2006

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