« Previous
Next »
Gastroenterology
Volume 128, Issue 4
, Pages 891-906
, April 2005
Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria
References
-
.
Microbial influences in inflammatory bowel disease
(role in pathogenesis and clinical implications)
.
In:
Sartor RB
, Sandborn WJ
editor.
Kirsner’s inflammatory bowel diseases
. 6th ed. London: Elsevier; 2004;p. 138–162
- . Inflammatory bowel disease . N Engl J Med . 2002;347:417–429
- . Inflammatory bowel disease (etiology and pathogenesis) . Gastroenterology . 1998;115:182–205
-
.
Animal models of intestinal inflammation
.
In:
Sartor RB
, Sandborn WJ
editor.
Kirsner’s inflammatory bowel diseases
. 6th ed. London: Elsevier; 2004;p. 120–137
-
.
The immunology of mucosal models of inflammation
.
Ann Rev Immunol
. 2002;20:495–549
- . Inflammatory bowel disease-like enteritis and caecitis in a senescence accelerated mouse P1/Yit strain . Gut . 1998;43:71–78
- . T cell receptor-alpha beta–deficient mice fail to develop colitis in the absence of a microbial environment . Am J Pathol . 1997;150:91–97
- . Interleukin-10 deficient mice develop chronic enterocolitis . Cell . 1993;75:263–274
- . Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice . Infect Immun . 1998;66:5224–5231
- . Continuous stimulation by normal luminal bacteria is essential for the development and perpetuation of colitis in TGϵ26 mice . Gastroenterology . 2001;120:900–913
- . The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats . J Exp Med . 1994;180:2359–2364
- . CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice (increased T helper cell type 1 response and ability to transfer disease) . J Exp Med . 1998;187:855–864
- . Antibiotics with a selective aerobic or anaerobic spectrum have different therapeutic activities in various regions of the colon in interleukin 10 gene deficient mice . Gut . 2003;52:1721–1727
- . Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLAB27/human β2 microglobulin transgenic rats . J Clin Invest . 1996;98:945–953
- . Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli . Infect Immun . 1999;67:2969–2974
- . Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4 (+) TH1-like responses . J Clin Invest . 1996;98:1010–1020
- . Helicobacter hepaticus does not induce or potentiate colitis in interleukin-10 deficient mice . Infect Immun . 2000;68:5107–5113
- . Enterococcus faecalis induces inflammatory bowel disease in interleukin-10 knockout mice . Am J Pathol . 2002;160:2253–2257
- . Effect of bacterial monoassociation on tolerance and intestinal inflammation in IL-10 gene-deficient mice . (abstr) Gastroenterology . 2001;120:A517
- . Bacterial association leads to a rapid inflammatory response and development of an intestinal inflammation in germfree IL-10 gene-deficient mice . (abstr) Gastroenterology . 2001;120:A521
- . The Crohn’s disease-associated bacterial protein I2 is a novel T cell superantigen . Immunity . 2001;15:149–158
- . Pseudomonas fluorescens encodes the Crohn’s disease-associated I2 sequence and T-cell superantigen . Infect Immun . 2002;70:6567–6575
- . Comparison of Bacteroides vulgatus strains in the enhancement of experimental ulcerative colitis . Infect Immun . 1987;55:835–836
- . Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn’s disease . J Clin Invest . 2001;107:695–702
- . Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements (implications for joint and gut-associated immunopathologies) . Immunity . 1999;10:387–398
- . Emergence of perianal fistulizing disease in the SAMP1/YitFc mouse, a spontaneous model of chronic ileitis . Gastroenterology . 2003;124:972–982
- . Mucosal flora in inflammatory bowel disease . Gastroenterology . 2002;122:44–54
- . Isolation of Enterococcus faecalis clinical isolates that efficiently adhere to human bladder carcinoma T24 cells and inhibition of adhesion by fibronectin and trypsin treatment . Infect Immun . 1999;67:1585–1592
- . Aggregation substance increases adherence and internalization, but not translocation, of Enterococcus faecalis through different intestinal epithelial cells in vitro . Infect Immun . 2000;68:6044–6048
- . Evidence for the translocation of Enterococcus faecalis across the mouse intestinal tract . J Infect Dis . 1990;162:82–90
- . Identification of a novel bacterial sequence associated with Crohn’s disease . Gastroenterology . 2000;119:23–31
- . Monoassociation of SCID mice with Helicobacter muridarum, but not four other enterics, provokes IBD upon receipt of T cells . Gastroenterology . 2002;122:1346–1354
- . Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic interleukin-2-deficient mice . Gastroenterology . 2003;125:162–177
- . Distinct inflammatory mechanisms mediate early versus late colitis in mice . Gastroenterology . 2002;122:94–105
- . T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin-10 deficient mice . J Exp Med . 1996;184:241–251
- . T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice . J Exp Med . 1995;182:1567–1572
- . TGF-β1-activated Smad signaling inhibits non-pathogenic Gram-negative bacteria-induced NF-κB recruitment to the IL-6 gene promoter through modulation of histone acetylation in intestinal epithelial cells . J Biol Chem . 2003;278:23851–23860
- . P-selectin and P-selectin glycoprotein ligand 1 are major determinants for Th1 cell recruitment to nonlymphoid effector sites in the intestinal lamina propria . J Exp Med . 2003;198:369–377
- . T cell specificity and cross reactivity towards enterobacteria, Bacteroides, Bifidobacterium, and antigens from resident intestinal flora in humans . Gut . 1999;44:812–818
- . Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD) . Clin Exp Immunol . 1995;102:448–455
- . Presence of enteroadherent E. coli strains in ileal mucosa of patients with Crohn’s disease . Gastroenterology . 1998;115:1405–1413
- . An immunocytochemical search for infectious agents in Crohn’s disease . Mod Pathol . 1993;6:212–219
- . Combination ciprofloxacin and metronidazole for active Crohn’s disease . Can J Gastroenterol . 1998;12:53–56
- Double blind, placebo controlled trial of metronidazole in Crohn’s disease . Gut . 1991;32:1071–1075
- . Combined budesonide and antibiotic therapy for active Crohn’s disease (a randomized controlled trial) . Gastroenterology . 2002;123:33–34
Supported by NIH Grant R01 DK53347 (to R.B.S. and S.L.T.), NIH Grant T32 DK07634 (to S.C.K.), the Center for Gastrointestinal Biology and Disease (NIH Grant P30 DK34987) pilot feasibility grant (to S.C.K.), and Core Laboratories, Crohn’s and Colitis Foundation of America research grants (to R.B.S. and E.J.B.) and research fellowship award (to S.C.K.).
PII: S0016-5085(05)00178-2
doi: 10.1053/j.gastro.2005.02.009
© 2005 American Gastroenterological Association. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Gastroenterology
Volume 128, Issue 4
, Pages 891-906
, April 2005

