Gastroenterology
Volume 128, Issue 1 , Pages 108-120 , January 2005

Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis

  • Fiona Oakley

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • Muriel Meso

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • John P. Iredale

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • Karen Green

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • Carylyn J. Marek

      Affiliations

    • Department of Molecular and Cell Biology, University of Aberdeen, Aberdeen, Scotland
  • ,
  • Xiaoying Zhou

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • Michael J. May

      Affiliations

    • Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
  • ,
  • Harry Millward-Sadler

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
  • ,
  • Matthew C. Wright

      Affiliations

    • Department of Molecular and Cell Biology, University of Aberdeen, Aberdeen, Scotland
  • ,
  • Derek A. Mann

      Affiliations

    • Liver Group, Division of Infection, Inflammation & Repair, University of Southampton, School of Medicine, Southampton General Hospital, Southampton, England
    • Corresponding Author InformationAddress requests for reprints to: Derek A. Mann, PhD, Liver Group, Level D, South Academic Block, Southampton General Hospital, Southampton SO16 6YD, United Kingdom; fax: (44) 23-80-79-8519.

Received 6 January 2004 ,Accepted 16 September 2004.

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 Supported by the Wellcome Trust (050443/Z and 068524/Z/02/Z), the UK Medical Research Council (Co-operative Group Grant component Grant G9900279), and the Children’s Liver Disease Foundation. J.P.I. is an Medical Research Council senior clinician fellow.

PII: S0016-5085(04)01847-5

doi: 10.1053/j.gastro.2004.10.003

Gastroenterology
Volume 128, Issue 1 , Pages 108-120 , January 2005