Gastroenterology
Volume 118, Issue 4 , Pages 661-669, April 2000

Long-term omeprazole treatment in resistant gastroesophageal reflux disease: Efficacy, safety, and influence on gastric mucosa☆☆☆

  • Elly C. Klinkenberg-Knol

      Affiliations

    • Department of Gastroenterology, Free University Hospital, Amsterdam, The Netherlands
    • ,
  • Frits Nelis

      Affiliations

    • Department of Gastroenterology, Sophia Hospital, Zwolle, The Netherlands
    • ,
  • John Dent

      Affiliations

    • Department of Gastrointestinal Medicine, Royal Adelaide Hospital, Adelaide, Australia
    • ,
  • Pleun Snel

      Affiliations

    • Department of Gastroenterology, Slotervaart Hospital, Amsterdam, The Netherlands
    • ,
  • Brent Mitchell

      Affiliations

    • Department of Gastroenterology, Launceston Hospital, Launceston, Tasmania
    • ,
  • Peter Prichard

      Affiliations

    • Department of Gastroenterology and Hepatology, Epworth Hospital, Victoria, Australia
    • ,
  • David Lloyd

      Affiliations

    • St. Joseph's Health Centre, London, Ontario, Canada
    • ,
  • Niilo Havu

      Affiliations

    • Department of Safety Assessment, AstraZeneca, Södertälje, Sweden; and Departments of
    • ,
  • Madeline H. Frame

      Affiliations

    • Clinical Science
    • ,
  • Jonas Romàn

      Affiliations

    • Biostatistics
    • ,
  • Anders Walan

      Affiliations

    • Gastrointestinal Management and Strategy, AstraZeneca, Mölndal, Sweden
    • ,
  • Long–Term Study Group

Received 9 June 1999; accepted 10 December 1999.

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    • ☆ Address requests for reprints to: Elly C. Klinkenberg-Knol, M.D., Ph.D., Department of Gastroenterology, Free University Hospital, De Boelelaan 1117, 1007 MB, Amsterdam, The Netherlands. e-mail: EC.Klinkenberg@azvu.nl; fax: (31) 20-444-0554.

    ☆☆ Supported by Astra Hässle AB, Mölndal, Sweden.

    PII: S0016-5085(00)70135-1

    Gastroenterology
    Volume 118, Issue 4 , Pages 661-669, April 2000