Gastroenterology
Volume 138, Issue 3 , Pages 1055-1067.e4 , March 2010

Apoptosis Signal-Regulating Kinase 1 Regulates Colitis and Colitis-Associated Tumorigenesis by the Innate Immune Responses

  • Yoku Hayakawa

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Yoshihiro Hirata

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Hayato Nakagawa

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Kei Sakamoto

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • Division of Gastroenterology, Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan
    • ,
  • Yohko Hikiba

      Affiliations

    • Division of Gastroenterology, Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan
    • ,
  • Motoyuki Otsuka

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Hideaki Ijichi

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Tsuneo Ikenoue

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Keisuke Tateishi

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Masao Akanuma

      Affiliations

    • Division of Gastroenterology, Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan
    • ,
  • Keiji Ogura

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Haruhiko Yoshida

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Hidenori Ichijo

      Affiliations

    • Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan
    • ,
  • Masao Omata

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • ,
  • Shin Maeda

      Affiliations

    • Department of Gastroenterology, University of Tokyo, Tokyo, Japan
    • Corresponding Author InformationReprint requests Address requests for reprints to: Shin Maeda, Department of Gastroenterology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655. fax: (81) 3-3814-0021

Received 12 June 2009 ,Accepted 12 November 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding S.M. and K.O. were supported by grants-in-aid from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (19390205).

PII: S0016-5085(09)02031-9

doi: 10.1053/j.gastro.2009.11.015

Gastroenterology
Volume 138, Issue 3 , Pages 1055-1067.e4 , March 2010

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