Gastroenterology
Volume 137, Issue 6 , Pages 2136-2145.e7 , December 2009

Retinoic Acid Receptor Antagonists Inhibit miR-10a Expression and Block Metastatic Behavior of Pancreatic Cancer

  • Frank Ulrich Weiss

      Affiliations

    • Universitätsklinikum Greifswald, Klinik für Innere Medizin A, Greifswald, Germany
  • ,
  • Ines J. Marques

      Affiliations

    • Institute of Biology, Department of Integrative Zoology, University of Leiden, AL Leiden, The Netherlands
  • ,
  • Joost M. Woltering

      Affiliations

    • Institute of Biology, Department of Integrative Zoology, University of Leiden, AL Leiden, The Netherlands
  • ,
  • Danielle H. Vlecken

      Affiliations

    • Institute of Biology, Department of Integrative Zoology, University of Leiden, AL Leiden, The Netherlands
  • ,
  • Ali Aghdassi

      Affiliations

    • Universitätsklinikum Greifswald, Klinik für Innere Medizin A, Greifswald, Germany
  • ,
  • Lars Ivo Partecke

      Affiliations

    • Universitätsklinikum Greifswald Abteilung für Allgemein-, Viszeral-, Thorax- und Gefäβchirurgie, Greifswald, Germany
  • ,
  • Claus–Dieter Heidecke

      Affiliations

    • Universitätsklinikum Greifswald Abteilung für Allgemein-, Viszeral-, Thorax- und Gefäβchirurgie, Greifswald, Germany
  • ,
  • Markus M. Lerch

      Affiliations

    • Universitätsklinikum Greifswald, Klinik für Innere Medizin A, Greifswald, Germany
  • ,
  • Christoph P. Bagowski

      Affiliations

    • Institute of Biology, Department of Integrative Zoology, University of Leiden, AL Leiden, The Netherlands
    • Corresponding Author InformationReprint requests Address requests for reprints to: Christoph P. Bagowski, MD, Institute of Biology, University of Leiden, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands. fax: (31) (0)71-527-4999

Received 24 July 2008 ,Accepted 24 August 2009.

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 Conflicts of interest The authors disclose no conflicts.

 Funding This work was supported by grants from the Portuguese foundation for Science and Technology (SFRH/BD/27262/2006), the Deutsche Krebshilfe (10-2031-Le), (FVMM) University Greifswald, and by the Alfried Krupp Graduate School of Tumorbiology.

PII: S0016-5085(09)01557-1

doi: 10.1053/j.gastro.2009.08.065

Gastroenterology
Volume 137, Issue 6 , Pages 2136-2145.e7 , December 2009