Gastroenterology
Volume 137, Issue 4 , Pages 1197-1201 , October 2009

Capsule Endoscopy and Deep Enteroscopy: Indications for the Practicing Clinician

  • Lauren B. Gerson

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Lauren B. Gerson, MD, MSc, Division of Gastroenterology and Hepatology, A149, 300 Pasteur Drive, Stanford, CA 94305-5202; phone: (650) 736-0431; fax (650) 723-8305

References 

  1. Rockey DC. Occult gastrointestinal bleeding. N Engl J Med. 1999;341:38–46
  2. Hartmann D, Schmidt H, Bolz G, et al. A prospective two-center study comparing wireless capsule endoscopy with intraoperative enteroscopy in patients with obscure GI bleeding. Gastrointest Endosc. 2005;61:826–832
  3. Pennazio M, Santucci R, Rondonotti E, et al. Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: report of 100 consecutive cases. Gastroenterology. 2004;126:643–653
  4. Rondonotti E, Pennazio M, Toth E, et al. Small-bowel neoplasms in patients undergoing video capsule endoscopy: a multicenter European study. Endoscopy. 2008;40:488–495
  5. Yamamoto H, Kita H, Sunada K, et al. Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases. Clin Gastroenterol Hepatol. 2004;2:1010–1016
  6. Costamagna G, Shah SK, Riccioni ME, et al. A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease. Gastroenterology. 2002;123:999–1005
  7. Huprich JE, Fletcher JG, Alexander JA, et al. Obscure gastrointestinal bleeding: evaluation with 64-section multiphase CT enterography—initial experience. Radiology. 2008;246:562–571
  8. Masselli G, Casciani E, Polettini E, et al. Comparison of MR enteroclysis with MR enterography and conventional enteroclysis in patients with Crohn's disease. Eur Radiol. 2008;18:438–447
  9. Gerber J, Bergwerk A, Fleischer D. A capsule endoscopy guide for the practicing clinician: technology and troubleshooting. Gastrointest Endosc. 2007;66:1188–1195
  10. Cave DR, Fleischer DE, Leighton JA, et al. A multicenter randomized comparison of the Endocapsule and the Pillcam SB. Gastrointest Endosc. 2008;68:487–494
  11. Hartmann D, Eickhoff A, Damian U, et al. Diagnosis of small-bowel pathology using paired capsule endoscopy with two different devices: a randomized study. Endoscopy. 2007;39:1041–1045
  12. Li F, Gurudu SR, De Petris G, et al. Retention of the capsule endoscope: a single-center experience of 1000 capsule endoscopy procedures. Gastrointest Endosc. 2008;68:174–180
  13. Cheifetz AS, Kornbluth AA, Legnani P, et al. The risk of retention of the capsule endoscope in patients with known or suspected Crohn's disease. Am J Gastroenterol. 2006;101:2218–2222
  14. Pennazio M, Eisen G, Goldfarb N. ICCE consensus for obscure gastrointestinal bleeding. Endoscopy. 2005;37:1046–1050
  15. Mehdizadeh S, Ross A, Gerson L, et al. What is the learning curve associated with double-balloon enteroscopy? (Technical details and early experience in 6 U.S. tertiary care centers). Gastrointest Endosc. 2006;64:740–750
  16. Fry LC, Bellutti M, Neumann H, et al. Incidence of bleeding lesions within reach of conventional upper and lower endoscopes in patients undergoing double balloon enteroscopy for obscure GI bleeding. Aliment Pharmacol Ther. 2009;29:342–349
  17. Saurin JC, Delvaux M, Gaudin JL, et al. Diagnostic value of endoscopic capsule in patients with obscure digestive bleeding: blinded comparison with video push-enteroscopy. Endoscopy. 2003;35:576–584
  18. Apostolopoulos P, Papanikolaou IS, Kalantzis N. Capsule endoscopy in obscure occult vs. obscure overt GI bleeding. Gastrointest Endosc. 2005;61:187–188
  19. Bresci G, Parisi G, Bertoni M, et al. The role of video capsule endoscopy for evaluating obscure gastrointestinal bleeding: usefulness of early use. J Gastroenterol. 2005;40:256–259
  20. Triester SL, Leighton JA, Leontiadis GI, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with non-stricturing small bowel Crohn's disease. Am J Gastroenterol. 2006;101:954–964
  21. Clarke JO, Giday SA, Magno P, et al. How good is capsule endoscopy for detection of periampullary lesions? (Results of a tertiary-referral center). Gastrointest Endosc. 2008;68:267–272
  22. Solem CA, Loftus EV, Fletcher JG, et al. Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial. Gastrointest Endosc. 2008;68:255–266
  23. Cheon JH, Kim YS, Lee IS, et al. Can we predict spontaneous capsule passage after retention? (A nationwide study to evaluate the incidence and clinical outcomes of capsule retention). Endoscopy. 2007;39:1046–1052
  24. Lee BI, Choi H, Choi KY, et al. Retrieval of a retained capsule endoscope by double-balloon enteroscopy. Gastrointest Endosc. 2005;62:463–465
  25. Herrerias JM, Leighton JA, Costamagna G, et al. Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy. Gastrointest Endosc. 2008;67:902–909
  26. Culliford A, Daly J, Diamond B, et al. The value of wireless capsule endoscopy in patients with complicated celiac disease. Gastrointest Endosc. 2005;62:55–61
  27. Iaquinto G, Fornasarig M, Quaia M, et al. Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis. Gastrointest Endosc. 2008;67:61–67
  28. Mata A, Llach J, Castells A, et al. A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary GI polyposis syndromes. Gastrointest Endosc. 2005;61:721–725
  29. Caspari R, von Falkenhausen M, Krautmacher C, et al. Comparison of capsule endoscopy and magnetic resonance imaging for the detection of polyps of the small intestine in patients with familial adenomatous polyposis or with Peutz-Jeghers' syndrome. Endoscopy. 2004;36:1054–1059
  30. Bardan E, Nadler M, Chowers Y, et al. Capsule endoscopy for the evaluation of patients with chronic abdominal pain. Endoscopy. 2003;35:688–689
  31. Sugano KYH, Kita H. Double-balloon endoscopy: theory and practice. New YorK: Springer; 2006;
  32. Yamamoto H, Sekine Y, Sato Y, et al. Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc. 2001;53:216–220
  33. Gerson LB, Flodin JT, Miyabayashi K. Balloon-assisted enteroscopy: technology and troubleshooting. Gastrointest Endosc. 2008;68:1158–1167
  34. Hartmann D, Eickhoff A, Tamm R, et al. Balloon-assisted enteroscopy using a single-balloon technique. Endoscopy. 2007;39(Suppl 1):E276
  35. Akerman PA, Agrawal D, Cantero D, et al. Spiral enteroscopy with the new DSB overtube: a novel technique for deep peroral small-bowel intubation. Endoscopy. 2008;40:974–978
  36. Ross A, Mehdizadeh S, Tokar J, et al. Double balloon enteroscopy detects small bowel mass lesions missed by capsule endoscopy. Dig Dis Sci. 2008;53:2140–2143
  37. Lai LH, Wong GL, Chow DK, et al. Long-term follow-up of patients with obscure gastrointestinal bleeding after negative capsule endoscopy. Am J Gastroenterol. 2006;101:1224–1228
  38. Gerson L, Kamal A. Cost-effectiveness analysis of management strategies for obscure GI bleeding. Gastrointest Endosc. 2008;68:920–936
  39. Mensink PB, Haringsma J, Kucharzik T, et al. Complications of double balloon enteroscopy: a multicenter survey. Endoscopy. 2007;39:613–615
  40. May A, Nachbar L, Pohl J, et al. Endoscopic interventions in the small bowel using double balloon enteroscopy: feasibility and limitations. Am J Gastroenterol. 2007;102:527–535
  41. Tominaga K, Iida T, Nakamura Y, et al. Small intestinal perforation of endoscopically unrecognized lesions during peroral single-balloon enteroscopy. Endoscopy. 2008;40(Suppl 2):E213–E214
  42. Gerson LB, Tokar J, Chiorean M, et al. Complications associated with double balloon enteroscopy at 9 US centers. Clin Gastroenterol Hepatol. 2009;[In Press]
  43. Raju GS, Gerson L, Das A, et al. American Gastroenterological Association (AGA) Institute technical review on obscure gastrointestinal bleeding. Gastroenterology. 2007;133:1697–1717
  44. Pasha SF, Leighton JA, Das A, et al. Double-balloon enteroscopy and capsule endoscopy have comparable diagnostic yield in small-bowel disease: a meta-analysis. Clin Gastroenterol Hepatol. 2008;6:671–676

 Conflicts of interest Dr Gerson discloses that she has received equipment, grant support, and speaking honorarium from Fujinon, Inc, and speaking honorarium from Given Imaging, Inc.

PII: S0016-5085(09)01501-7

doi: 10.1053/j.gastro.2009.08.035

Gastroenterology
Volume 137, Issue 4 , Pages 1197-1201 , October 2009

Article Tools

* Image Usage & Resolution