Gastroenterology
Volume 137, Issue 4 , Pages 1535-1536 , October 2009

Patients With Drug-Induced Microscopic Colitis Should Not Be Included in Controlled Trials Assessing the Efficacy of Anti-Inflammatory Drugs in Microscopic Colitis

  • Laurent Beaugerie

      Affiliations

    • Department of Gastroenterology, Hôpital Saint-Antoine and UPMC University of Paris, Paris, France
    • ,
  • Darrell S. Pardi

      Affiliations

    • Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota

References 

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  2. Miehlke S, Madisch A, Bethke B, et al. Oral budesonide for maintenance treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial. Gastroenterology. 2008;135:1510–1516
  3. Beaugerie L, Luboinski J, Brousse N, et al. Drug induced lymphocytic colitis. Gut. 1994;35:426–428
  4. Thomson RD, Lestina LS, Bensen SP, et al. Lansoprazole-associated microscopic colitis: a case series. Am J Gastroenterol. 2002;97:2908–2913
  5. Fernandez-Banares F, Esteve M, Espinos JC, et al. Drug consumption and the risk of microscopic colitis. Am J Gastroenterol. 2007;102:324–330
  6. Beaugerie L, Pardi DS. Review article: drug-induced microscopic colitis—proposal for a scoring system and review of the literature. Aliment Pharmacol Ther. 2005;22:277–284
  7. Macedo AF, Marques FB, Ribeiro CF, et al. Causality assessment of adverse drug reactions: comparison of the results obtained from published decisional algorithms and from the evaluations of an expert panel, according to different levels of imputability. J Clin Pharm Ther. 2003;28:137–143
  8. Begaud B, Evreux JC, Jouglard J, et al. [Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France]. Therapie. 1985;40:111–118
  9. Marteau P, Lavergne-Slove A, Lemann M, et al. Primary ileal villous atrophy is often associated with microscopic colitis. Gut. 1997;41:561–564
  10. Colombel JF, Loftus EV, Tremaine WJ, et al. The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients. Gastroenterology. 2004;126:19–31

 Conflicts of interest The authors disclose no conflicts.

PII: S0016-5085(09)01396-1

doi: 10.1053/j.gastro.2009.04.067

Gastroenterology
Volume 137, Issue 4 , Pages 1535-1536 , October 2009

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