This Month in Gastroenterology

Survival over 45 years of follow-up in 14 subjects with undiagnosed celiac disease and 9,076 seronegative persons in the WAFB cohort.

Repeated measure analysis with mixed effects model. (A) Mean BUN levels among survivors versus nonsurvivors. (B) Mean hemoglobin levels among survivors versus nonsurvivors. Mean levels along with 95% confidence limits are depicted.

Compounds that cause gastrin release in isolated G-cells. (Left) Constituents of food including the “sweet” tasting amino acids (tyrosine), sweet and bitter tastants and pain/heat transducers (capsaicin) stimulate gastrin secretion. (Right) Bacteria also stimulate gastrin secretion through LPS.

Quantification of the volume of autolysosomes (expressed as percentage of the total acinar volume) from electron microscopy. Data plotted as mean values ± standard error of the mean of 4 individuals per group. *P < .0001 versus pair-fed 24 hours after LPS. **P < .0001 versus alcohol-fed rats; ***P < .0001 versus alcohol-fed rats 24 hours after LPS. ****P < .0044 versus alcohol-fed rats 24 hours after LPS.