Gastroenterology
Volume 136, Issue 7 , Pages 2334-2344.e1 , June 2009

Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis

  • Fiona Oakley

      Affiliations

    • Liver Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Victoria Teoh

      Affiliations

    • Liver Group, University of Southampton, Southampton, United Kingdom
    • ,
  • Gemma Ching–A–Sue

      Affiliations

    • Liver Group, University of Southampton, Southampton, United Kingdom
    • ,
  • Ramon Bataller

      Affiliations

    • Liver Unit, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    • ,
  • Jordi Colmenero

      Affiliations

    • Liver Unit, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    • ,
  • Julie R. Jonsson

      Affiliations

    • University of Queensland, School of Medicine, Southern Division, Princess Alexandra Hospital, Queensland, Australia
    • ,
  • Aristides G. Eliopoulos

      Affiliations

    • Laboratory of Molecular and Cellular Biology, Division of Basic Sciences, the University of Crete Medical School, Crete, Greece
    • ,
  • Martha R. Watson

      Affiliations

    • Liver Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Derek Manas

      Affiliations

    • Liver Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • ,
  • Derek A. Mann

      Affiliations

    • Liver Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Corresponding Author InformationReprint requests Address requests for reprints to: Derek A. Mann, PhD, Liver Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom. fax: (44) 19122 25455

Received 23 July 2008 ,Accepted 26 February 2009.

References 

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 Conflicts of interest The authors disclose no conflicts.

 Funding Supported by grants from the British Liver Trust and the UK Medical Research Council (to D.A.M.).

PII: S0016-5085(09)00369-2

doi: 10.1053/j.gastro.2009.02.081

Gastroenterology
Volume 136, Issue 7 , Pages 2334-2344.e1 , June 2009

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