« Previous
Next »
Gastroenterology
Volume 136, Issue 5
, Pages 1659-1668
, May 2009
Interaction of Cyclooxygenase-2 Variants and Smoking in Pancreatic Cancer: A Possible Role of Nucleophosmin
References
- Pancreatic cancer. Lancet. 2004;363:1049–1057
- Molecular aspects of carcinogenesis in pancreatic cancer. Hepatobiliary Pancreat Dis Int. 2008;7:345–356
- . Smoking—a trigger for chronic inflammation and cancer development in the pancreas. Am J Gastroenterol. 2006;101:160–162
- . Epidemiology and risk factors for pancreatic cancer. Best Pract Res Clin Gastroenterol. 2006;20:197–209
- Inflammatory mechanisms contributing to pancreatic cancer development. Ann Surg. 2004;239:763–769
- Role of inflammation in pancreatic carcinogenesis and the implications for future therapy. Pancreatology. 2005;5:514–529
- Familial pancreatic cancer. Cancer J. 2001;7:266–273
- . The hereditary spectrum of pancreatic cancer: the Edmonton experience. Can J Gastroenterol. 2004;18:17–21
- . The role of genetic factors in the etiology of pancreatic adenocarcinoma: an update. Cancer Invest. 2001;19:65–75
- . Gene-environment interactions in pancreatic cancer. Pancreatology. 2001;1:472–476
- . The role of cyclooxygenases in inflammation, cancer, and development. Oncogene. 1999;18:7908–7916
- . Non-steroidal anti-inflammatory drugs for cancer prevention: promise, perils and pharmacogenetics. Nat Rev Cancer. 2006;6:130–140
- Cyclooxygenase-2 is overexpressed in chronic pancreatitis. Pancreas. 2002;25:26–30
- Cyclooxygenase-2 expression associated with severity of PanIN lesions: a possible link between chronic pancreatitis and pancreatic cancer. Pancreatology. 2005;5:361–369
- Cyclooxygenase-2 expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasia: an immunohistochemical analysis with automated cellular imaging. Am J Clin Pathol. 2002;118:194–201
- Cyclooxygenase-2 expression correlates with poor prognosis in pancreatic cancer. J Clin Pathol. 2006;59:382–386
- Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res. 1999;59:987–990
- The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. J Cancer Res Clin Oncol. 2002;128:525–532
- . Aspirin may lower risk of pancreatic cancer. Lancet Oncol. 2002;3:518
- Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: a phase II trial. Cancer Chemother Pharmacol. 2006;57:185–190
- . Regulation of COX-2 expression in human cancers. Prog Exp Tumor Res. 2003;37:52–71
- Transcriptional regulation of cyclooxygenase 2 by bradykinin and interleukin-1β in human airway smooth muscle cells: involvement of different promoter elements, transcription factors, and histone h4 acetylation. Mol Cell Biol. 2003;23:9233–9244
- Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology. 2005;129:565–576
- Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer. Clin Gastroenterol Hepatol. 2005;3:743–751
- Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263–265
- Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered. 2003;55:56–65
- Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler Thromb Vasc Biol. 2002;22:1631–1636
- Role of nucleophosmin in embryonic development and tumorigenesis. Nature. 2005;437:147–153
- . Functional effects and gender association of COX-2 gene polymorphism G-765C in bronchial asthma. J Allergy Clin Immunol. 2004;114:248–253
- . Association of COX-2 gene haplotypes with prostaglandins production in bronchial asthma. J Allergy Clin Immunol. 2005;116:221–223
- . Mechanisms of smoking-related lung and pancreatic adenocarcinoma development. Nat Rev Cancer. 2002;2:455–463
- A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. J Natl Cancer Inst. 2002;94:297–306
- Cigarette smoke condensate activates nuclear transcription factor-κB through phosphorylation and degradation of IκB(α): correlation with induction of cyclooxygenase-2. Carcinogenesis. 2002;23:1511–1518
- Nucleophosmin and cancer. Nat Rev Cancer. 2006;6:493–505
- . Playing both sides: nucleophosmin between tumor suppressor and oncogenesis. J Cell Biol. 2008;182:7–9
- Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse. Blood. 2008;111:3859–3862
- COX-2 CA-haplotype is a risk factor for the development of esophageal adenocarcinoma. Am J Gastroenterol. 2007;102:2373–2379
- Functional polymorphisms in the cyclooxygenase 2 (COX-2) gene and risk of breast cancer in a Chinese population. J Toxicol Environ Health A. 2007;70:908–915
- Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer. Carcinogenesis. 2007;28:1197–1201
Conflicts of interest The authors disclose no conflicts.
Funding Supported by the National Natural Science Foundation grant 30471957 and the State Key Basic Research Program grant 2004CB518701.
PII: S0016-5085(09)00185-1
doi: 10.1053/j.gastro.2009.01.071
© 2009 AGA Institute. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Gastroenterology
Volume 136, Issue 5
, Pages 1659-1668
, May 2009

