Gastroenterology
Volume 136, Issue 3 , Pages 760-763 , March 2009

Nitazoxanide: Beyond Parasites Toward a Novel Agent for Hepatitis C

  • Jama M. Darling

      Affiliations

    • Corresponding Author InformationReprint requests Address requests for reprints to: Jama M. Darling, MD, University of North Carolina, CB# 7584, Room 8015 Burnett-Womack Building, Chapel Hill, NC 27599-7584
    • ,
  • Michael W. Fried

  • Image Result

    NTZ increases phosphorylation of PKR and induces eIF2a, which ultimately inhibits translation of viral RNA.

    NTZ increases phosphorylation of PKR and induces eIF2a, which ultimately inhibits translation of viral RNA.

 Conflicts of interest Michael W. Fried receives grant support from several companies that make competing products including Roche, Vertex, Human Genome Sciences, Wyeth, and Tibotec. He has no interest in or support from Romark, the sponsor of the study this editorial refers to.

 Dr Darling discloses no conflicts.

PII: S0016-5085(09)00050-X

doi: 10.1053/j.gastro.2009.01.020

Gastroenterology
Volume 136, Issue 3 , Pages 760-763 , March 2009

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