Gastroenterology
Volume 136, Issue 2 , Pages 417-424, February 2009

A Magnetic Resonance Spectroscopy Study of Brain Glutamate in a Model of Plasticity in Human Pharyngeal Motor Cortex

  • Salil Singh

      Affiliations

    • Gastrointestinal Science, Salford Royal Hospital, Salford, United Kingdom
    • ,
  • Satish Mistry

      Affiliations

    • Gastrointestinal Science, Salford Royal Hospital, Salford, United Kingdom
    • ,
  • Samantha Jefferson

      Affiliations

    • Gastrointestinal Science, Salford Royal Hospital, Salford, United Kingdom
    • ,
  • Karen Davies

      Affiliations

    • Imaging Science and Biomedical Engineering, University of Manchester, United Kingdom
    • ,
  • John Rothwell

      Affiliations

    • Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College of London, United Kingdom
    • ,
  • Stephen Williams

      Affiliations

    • Imaging Science and Biomedical Engineering, University of Manchester, United Kingdom
    • ,
  • Shaheen Hamdy

      Affiliations

    • Gastrointestinal Science, Salford Royal Hospital, Salford, United Kingdom
    • Corresponding Author InformationAddress requests for reprints to: Shaheen Hamdy, MD, School of Translational Medicine–Gastrointestinal Sciences, University of Manchester, Clinical Sciences Building, Salford Royal Hospital, Salford, United Kingdom M6 8HD. fax: (44) 161-206-4364

Received 12 June 2008; accepted 30 October 2008. published online 11 November 2008.

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 Drs Singh and Mistry conducted the studies, analyzed the data, and helped write the article. Drs Jefferson and Davies helped analyze the MRS data. Professors Rothwell and Williams helped to conceptualize the study, interpret data analysis, and helped to write the article. Dr Hamdy conceptualized the study, helped in data interpretation, and in the writing of the article.

 The authors disclose the following: This work was funded in part by grants from the Medical Research Council (S.S., S.M., S.H., J.R., and S.W.), The Wellcome Trust (S.H., S.M., and S.W.), and the Stroke Association (S.J.).

PII: S0016-5085(08)02040-4

doi:10.1053/j.gastro.2008.10.087

Gastroenterology
Volume 136, Issue 2 , Pages 417-424, February 2009

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