Gastroenterology
Volume 135, Issue 6 , Pages 1953-1960, December 2008

A Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial of Etanercept in the Treatment of Alcoholic Hepatitis

  • Nicholas C. Boetticher

      Affiliations

    • Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota
    • ,
  • Craig J. Peine

      Affiliations

    • Division of Gastroenterology/Department of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota
    • ,
  • Paul Kwo

      Affiliations

    • Department of Medicine, Indiana University, Indianapolis, Indiana
    • ,
  • Gary A. Abrams

      Affiliations

    • Alabama Liver & Digestive Specialists, Montgomery, Alabama
    • ,
  • Tushar Patel

      Affiliations

    • Department of Medicine, Scott & White Clinic, Temple, Texas
    • ,
  • Bashar Aqel

      Affiliations

    • Division of Gastroenterology/Department of Medicine, Mayo Clinic, Scottsdale, Arizona
    • ,
  • Lisa Boardman

      Affiliations

    • Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota
    • ,
  • Gregory J. Gores

      Affiliations

    • Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota
    • ,
  • William S. Harmsen

      Affiliations

    • Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
    • ,
  • Craig J. McClain

      Affiliations

    • Departments of Medicine and Pharmacology & Toxicology, University of Louisville and Louisville VAMC, Louisville, Kentucky
    • ,
  • Patrick S. Kamath

      Affiliations

    • Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota
    • ,
  • Vijay H. Shah

      Affiliations

    • Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, Rochester, Minnesota
    • Corresponding Author InformationAddress requests for reprints to: Vijay Shah, MD, Miles and Shirley Fiterman Center for Digestive Diseases, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905. fax: (507) 255-6318

Received 28 April 2008; accepted 28 August 2008. published online 16 September 2008.

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    •  Supported by the NIH (R01 AA013933 to V.S.), the NIH funded Mayo Clinical Research Unit (CTSA), and Amgen (to V.S.), which provided study drug and partially defrayed costs for cytokine analyses that exceeded the NIH budget.

     The authors disclose the following: All analyses and writing were conducted at the Mayo Clinic. Authors have no other conflicts of interest to disclose.

    PII: S0016-5085(08)01669-7

    doi:10.1053/j.gastro.2008.08.057

    Gastroenterology
    Volume 135, Issue 6 , Pages 1953-1960, December 2008