Gastroenterology
Volume 133, Issue 1 , Pages 340-342 , July 2007

Irritable Bowel Syndrome: Shifting the Focus Toward the Gut Microbiota

  • Fergus Shanahan

      Affiliations

    • Corresponding Author InformationAddress requests for reprints to: Fergus Shanahan, MD, Professor and Chair, Department of Medicine and Director, Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland. fax (353) 21-4345300.

References 

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  5. Spiller R. Role of infection in irritable bowel syndrome. J Gastroenterol. 2007;42(Suppl XVII):41–47
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  9. O’Mahony L, McCarthy J, Kelly P, Hurley G, Luo F, Chen K, et al. Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. Gastroenterology. 2005;128:541–551
  10. O’Hara A, Shanahan F. The gut flora as a forgotten organ. EMBO Rep. 2006;7:688–693
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  14. Kassinen A, Krogius-Kurikka L, Mäkivuokko H, Rinttilä T, Paulin L, Corander J, et al. The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects. Gastroenterology. 2007;133:24–33
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  16. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, et al. Diversity of the human intestinal microbial flora. Science. 2005;308:1635–1638
  17. Gill SR, Pop M, DeBoy RT, Eckburg PB, Turnbaugh PJ, Samuel BS, et al. Metagenomic analysis of the human distal microbiome. Science. 2006;312:1355–1359
  18. Pennisi E. Massive microbial sequence project proposed. Science. 2007;315:1781

PII: S0016-5085(07)01012-8

doi: 10.1053/j.gastro.2007.05.030

Gastroenterology
Volume 133, Issue 1 , Pages 340-342 , July 2007

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