Gastroenterology
Volume 129, Issue 5 , Pages 1756-1780 , November 2005

American Gastroenterological Association Technical Review on the Evaluation of Dyspepsia

  • Nicholas J. Talley

      Affiliations

    • Division of Gastroenterology and Hepatology and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
    • Dr. Talley is a consultant for AstraZeneca, Novartis, Axcan, EB Med, Giaconda, Medscape, Solvay, Theravance, and Yamanouchi and received research support from Merck, Novartis, and TAP.
    • Corresponding Author InformationAddress requests for reprints to: Chair, Clinical Practice and Economics Committee, AGA National Office, c/o Membership Department, 4930 Del Ray Avenue, Bethesda, Maryland 20814. Fax: (301) 654-5920.
    • ,
  • Nimish B. Vakil

      Affiliations

    • University of Wisconsin Medical School, Madison, Wisconsin Marquette University College of Health Sciences, Milwaukee, Wisconsin
    • Dr. Vakil is a consultant for Meridian Diagnostics, Orexo, and AstraZeneca, and received research support from Janssen, AstraZeneca, and Novartis.
    • ,
  • Paul Moayyedi

      Affiliations

    • McMaster University, Hamilton, Ontario, Canada
    • Dr. Moayyedi is a consultant for AstraZeneca, Wyeth Laboratories, and Takeda. His Professorial Chair is also partially funded by an unrestricted donation from AstraZeneca.

  • Image Result

    Summary of randomized controlled trials of H pylori eradication versus placebo on the risk of more than mild chronic gastritis persisting. Heterogeneity chi-squared = 1.58 (d.f. = 2) P = .45.

    Summary of randomized controlled trials of H pylori eradication versus placebo on the risk of more than mild chronic gastritis persisting. Heterogeneity chi-squared = 1.58 (d.f. = 2) P = .45.

  • Image Result

    Forest plot of randomized controlled trials comparing PPI therapy with placebo in uninvestigated dyspepsia.

    Forest plot of randomized controlled trials comparing PPI therapy with placebo in uninvestigated dyspepsia.

  • Image Result

    Forest plot of randomized controlled trials comparing PPI with H2RA therapy in uninvestigated dyspepsia.

    Forest plot of randomized controlled trials comparing PPI with H2RA therapy in uninvestigated dyspepsia.

  • Image Result

    Forest plot of randomized trials of H pylori eradication versus placebo antibiotics in H pylori–positive patients with dyspepsia.

    Forest plot of randomized trials of H pylori eradication versus placebo antibiotics in H pylori–positive patients with dyspepsia.

  • Image Result

    Forest plot of randomized controlled trials of endoscopy versus empirical acid suppression in patients with dyspepsia.

    Forest plot of randomized controlled trials of endoscopy versus empirical acid suppression in patients with dyspepsia.

  • Image Result

    Forest plot of randomized trial of H pylori eradication versus endoscopy in patients with dyspepsia. Proportion of patients with cure of dyspepsia.

    Forest plot of randomized trial of H pylori eradication versus endoscopy in patients with dyspepsia. Proportion of patients with cure of dyspepsia.

  • Image Result

    Forest plot of randomized trial of H pylori eradication versus endoscopy in patients with dyspepsia. Proportion of patients who underwent endoscopy.

    Forest plot of randomized trial of H pylori eradication versus endoscopy in patients with dyspepsia. Proportion of patients who underwent endoscopy.

  • Image Result

    Forest plot of randomized controlled trials of PPI therapy versus placebo in patients with nonulcer dyspepsia.

    Forest plot of randomized controlled trials of PPI therapy versus placebo in patients with nonulcer dyspepsia.

  • Image Result

    Forest plot of randomized controlled trials of H pylori eradication therapy versus placebo antibiotics in H pylori–positive patients with nonulcer dyspepsia.

    Forest plot of randomized controlled trials of H pylori eradication therapy versus placebo antibiotics in H pylori–positive patients with nonulcer dyspepsia.

PII: S0016-5085(05)01818-4

doi: 10.1053/j.gastro.2005.09.020

Gastroenterology
Volume 129, Issue 5 , Pages 1756-1780 , November 2005

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