| | Editor's Essential Reading  Clinical—Alimentary TractWilliam J. Sandborn, Jaroslaw Regula, Brian G. Feagan, Elena Belousova, Njegica Jojic, Milan Lukas, Bruce Yacyshyn, Piotr Krzeski, Chyon–Hwa Yeh, Christi A. Messer, Stephen B. Hanauer
It is not clear what induction dose of mesalamine is optimal for treating patients with mildly and moderately active ulcerative colitis (UC). This study was conducted to determine the efficacy and safety of mesalamine 4.8 g/day compared with 2.4 g/day for the treatment of moderately active UC.
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Gastroenterology, the official journal of the AGA Institute, is the number one journal in the field of gastrointestinal disease and ranks in the top one percent of all biomedical journals.
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| Issue HighlightsClinical—Alimentary Tract |  |
Brennan Spiegel, Michael Camilleri, Roger Bolus, Viola Andresen, William D. Chey, Sheri Fehnel, Allen Mangel, Nicholas J. Talley, William E. Whitehead
| Clinical Advances in Liver, Pancreas, and Biliary Tract |  |
Mitchell L. Shiffman, Chihiro Morishima, Jules L. Dienstag, Karen L. Lindsay, John C. Hoefs, William M. Lee, Elizabeth C. Wright, Deepa Naishadham, Gregory T. Everson, Anna S. Lok, Adrian M. Di Bisceglie, Herbert L. Bonkovsky, Marc G. Ghany, HALT-C Trial Group
| Clinical—Liver, Pancreas, and Biliary Tract | |
Erik H.C.J. Buster, Bettina E. Hansen, George K.K. Lau, Teerha Piratvisuth, Stefan Zeuzem, Ewout W. Steyerberg, Harry L.A. Janssen
| Basic—Alimentary Tract |  |
Ling Zheng, Terrence E. Riehl, William F. Stenson
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Michael Scharl, Gisela Paul, Achim Weber, Barbara C. Jung, Michael J. Docherty, Martin Hausmann, Gerhard Rogler, Kim E. Barrett, Declan F. McCole
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Marco Metzger, Petra M. Bareiss, Timm Danker, Silvia Wagner, Joerg Hennenlotter, Elke Guenther, Florian Obermayr, Arnulf Stenzl, Alfred Koenigsrainer, Thomas Skutella, Lothar Just
| Basic—Liver, Pancreas, and Biliary Tract | |
Fouad Lafdil, Hua Wang, Ogyi Park, Weici Zhang, Yuki Moritoki, Shi Yin, Xin Yuan Fu, M. Eric Gershwin, Zhe–Xiong Lian, Bin Gao
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Frank Ulrich Weiss, Ines J. Marques, Joost M. Woltering, Danielle H. Vlecken, Ali Aghdassi, Lars Ivo Partecke, Claus–Dieter Heidecke, Markus M. Lerch, Christoph P. Bagowski
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Helen Carnaghan, Hugh Warren, Andrew Douds
Konstantinos Karmiris, Gilles Paintaud, Maja Noman, Charlotte Magdelaine–Beuzelin, Marc Ferrante, Danielle Degenne, Karolien Claes, Tamara Coopman, Nele Van Schuerbeek, Gert Van Assche, Severine Vermeire, Paul Rutgeerts
Douglas K. Rex, Viju P. Deenadayalu, Emely Eid, Thomas F. Imperiale, John A. Walker, Kuldip Sandhu, Anthony C. Clarke, Lybus C. Hillman, Akira Horiuchi, Lawrence B. Cohen, Ludwig T. Heuss, Shajan Peter, Christoph Beglinger, James A. Sinnott, Thomas Welton, Magdy Rofail, Iyad Subei, Rodger Sleven, Paul Jordan, John Goff, Patrick D. Gerstenberger, Harold Munnings, Martin Tagle, Brian W. Sipe, Till Wehrmann, Jack A. Di Palma, Kaitlin E. Occhipinti, Egidio Barbi, Andrea Riphaus, Stephen T. Amann, Gen Tohda, Timothy McClellan, Charles Thueson, John Morse, Nizam Meah
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Top 20 Most Cited Articles | |
|  | | Gastroenterology in the News
Gastroenterology has been featured in The New York Times, The New York Times Well Blog, the Guardian, Reuters, and on NPR! Read recent press releases.
Wanted: Editor-in-Chief for Gastroenterology
Applications due April 1, 2010. Term begins July 1, 2011. Read more.
New! Gastroenterology Supplemental Issue on Micronutrient Dosing
Read the November 2009 supplement to Gastroenterology, "Micronutrients in Parenteral Nutrition: Too Little or Too Much?". Based on proceedings from this year's annual American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Research Workshop, leading international experts present the latest information on correct dosages of parenteral vitamins and trace elements. AGA Institute Course on Sedation
To learn more about the administration of sedation, attend the AGA Institute’s course, Sedation Competencies for the Endoscopy Team: A Hands-on Course for Gastroenterologists and Nurses on Jan. 17, 2010 in Las Vegas. View details at www.gilearn.org/sedationcourse.
Join Gastroenterology and CGH on Facebook®
Readers of Gastroenterology and Clinical Gastroenterology and Hepatology (CGH) can now keep abreast of the journals' most recent and compelling research via the convenience of Facebook. Click here to learn more. More news and announcements |
Review
Celiac Disease: From Pathogenesis to Novel Therapies
Detlef Schuppan, Yvonne Junker, Donatella Barisani
Celiac disease has become one of the best-understood HLA-linked disorders. Although it shares many immunologic features with inflammatory bowel disease, celiac disease is uniquely characterized by (1) a defined trigger (gluten proteins from wheat and related
cereals), (2) the necessary presence of HLA-DQ2 or HLA-DQ8, and (3) the generation of circulating autoantibodies to the enzyme tissue transglutaminase (TG2).
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Clinical Challenges and Images in GI
An Unusual Cause of Hematochezia
Seth R. Sweetser, Louis M. Wong Kee Song
A 79-year-old man awoke with abdominal pain and rectal bleeding. His past history was notable for a splenectomy 6 years prior for immune thrombocytopenic purpura. He denied the use of antiplatelet and nonsteroidal anti-inflammatory drugs.
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